Euglena Gracilis Extract
INCI: EUGLENA GRACILIS EXTRACT
Reviewed by Emma · Last updated 2 Jun 2026
A microalgae extract rich in polysaccharides that may support skin hydration and resilience
Best For Skin Types
All, Dry, Sensitive, Mature
Addresses
Usage Frequency
Daily
Euglena Gracilis Extract products at Skintique
View all →What Is Euglena Gracilis Extract?
Euglena gracilis extract is derived from a single-celled freshwater microalga. The extract contains paramylon, a naturally occurring β-1,3-glucan polysaccharide, along with other bioactive compounds. In skincare formulations, it functions primarily as a skin conditioning agent.
The microalga accumulates paramylon as an energy reserve, which appears to be the component responsible for most of the extract's reported biological activity. This makes euglena gracilis extract a renewable, plant-derived ingredient suitable for formulators seeking natural alternatives to synthetic conditioning agents.
How It Works
The primary active component, paramylon, appears to work through multiple mechanisms. Research indicates it can interact with cellular signalling pathways — notably activating SIRT1, a protein involved in cellular stress response and longevity. This activation may help epidermal cells maintain their protective functions and respond more robustly to environmental challenges.
Additionally, paramylon exhibits antimicrobial and anti-inflammatory properties in laboratory settings, though the extent to which these translate to meaningful benefits in topical skincare remains an area requiring further investigation.
Clinical Evidence & References
Laboratory studies demonstrate that euglena gracilis extract and its isolated paramylon component can facilitate wound healing in animal models and activate cellular pathways associated with skin health. In particular, research shows it can increase SIRT1 expression in cell cultures and reduce excessive inflammatory markers during wound healing.
However, evidence in human skin is limited. Most existing data comes from in vitro studies or animal models rather than clinical trials on human volunteers. This means the ingredient's real-world efficacy in topical skincare products remains uncertain, though early indicators are encouraging enough to warrant its inclusion in some formulations.
How to Use
Euglena gracilis extract is typically incorporated into serums, moisturisers, and treatment products rather than used as a standalone ingredient. Apply to clean skin as directed by the specific product formulation. It pairs well with other hydrating and conditioning agents, though no specific interactions with other actives have been widely documented.
Safety & Precautions
Frequently Asked Questions
From the Clinic
Not sure what your skin actually needs?
Two minutes, a few questions, and we’ll point you at what matters — no guesswork.
Take the skin quizRelated Ingredients
Eucalyptus Globulus Leaf
A plant extract that may support skin barrier function and hydration
Eucalyptus Maculata Extract
A botanical extract with traditional use in skincare conditioning formulations
Eucommia Ulmoides Leaf Extract
A plant extract studied for its potential to support skin hydration and resilience
Eurya Japonica Extract
A plant extract with conditioning properties for everyday skincare
Euterpe Oleracea Fruit Oil
A lightweight botanical oil derived from açai berries with skin conditioning properties
Euterpe Oleracea Juice
A plant-derived conditioning agent that supports skin hydration and texture
Learn More About Skincare Ingredients
Explore our comprehensive ingredient glossary to understand what's in your products.
Browse All IngredientsShop Our Products
Find professional skincare solutions at Skintique.