Anti-Sebum

Gerotine/Hydrolyzed Dna

INCI: GEROTINE/HYDROLYZED DNA

Reviewed by Emma · Last updated 2 Jun 2026

Also known as: Gerotine/hydrolyzed Dna

A hydrolysed DNA ingredient with antioxidant properties for skin protection

Best For Skin Types

All, Oily, Combination, Mature

Addresses

Oxidative stress, Oil control, Environmental damage

Usage Frequency

Daily

What Is Gerotine/Hydrolyzed Dna?

Gerotine, also known as hydrolysed DNA, is a processed form of deoxyribonucleic acid (DNA) that has been broken down into smaller molecular fragments. This ingredient is derived from biological sources and functions primarily as an antioxidant in skincare formulations.

The hydrolysis process renders the DNA into a form suitable for topical application, allowing it to be incorporated into creams, serums, and other skincare products. As an antioxidant, it works to neutralise free radicals that can accumulate on and in the skin.

Benefits for Your Skin

How It Works

Hydrolysed DNA functions as an antioxidant by donating electrons to free radicals, thereby neutralising them before they can damage skin cells. Free radicals are unstable molecules generated through normal cellular processes, sun exposure, and environmental pollutants; their accumulation can accelerate visible signs of ageing.

The hydrolysis process breaks the DNA into smaller units, making it penetrable enough for topical use. Once applied, these fragments work on the skin surface and in the uppermost layers to provide antioxidant coverage.

Clinical Evidence & References

Research on hydrolysed DNA in skincare is limited. The ingredient is referenced in discussions of natural antioxidants and their potential role in skin health, though robust clinical trials demonstrating specific efficacy in topical formulations remain scarce.

While antioxidants as a category show evidence of benefit in protecting skin from oxidative damage, the particular performance of hydrolysed DNA compared to other antioxidant ingredients has not been extensively documented in peer-reviewed dermatological studies. Further investigation would help clarify its efficacy and optimal use in skincare.

How to Use

Hydrolysed DNA is typically incorporated into formulations that also contain other antioxidants and stabilising agents. Use products containing this ingredient as part of a broader antioxidant skincare routine, ideally in the morning to protect skin throughout the day. Layer before heavier creams or oils to allow proper absorption.

Safety & Precautions

Hydrolysed DNA is generally well-tolerated in topical skincare products. Those with sensitive skin or known allergies to DNA-derived ingredients should patch test before full application.

Frequently Asked Questions

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