Fragrance

Ginkgo Biloba Leaf Cell Extract

INCI: GINKGO BILOBA LEAF CELL EXTRACT

Reviewed by Emma · Last updated 14 Aug 2026

A plant extract with antioxidant and skin-soothing properties derived from ginkgo leaves

Best For Skin Types

All, Sensitive, Mature

Addresses

Redness, Sensitivity, Environmental damage

Usage Frequency

Daily

What Is Ginkgo Biloba Leaf Cell Extract?

Ginkgo biloba leaf cell extract is derived from the leaves of the ginkgo tree, one of the oldest living plant species. The extract contains a complex mixture of bioactive compounds, including flavonoids and biflavones, which are responsible for its skin-conditioning and protective functions in cosmetic formulations.

In skincare, this ingredient functions primarily as an antioxidant and skin protectant, helping to shield the skin from environmental stress whilst supporting the skin's natural resilience.

How It Works

Ginkgo biloba leaf extract contains bioactive compounds called biflavones, particularly ginkgetin, which appear to work by modulating inflammatory pathways in the skin. Research suggests these compounds may reduce the production of pro-inflammatory mediators, particularly through downregulation of COX-2 expression, which is involved in inflammation and inflammatory signalling.

The extract also functions as an antioxidant, helping to protect skin cells from oxidative stress caused by environmental factors such as pollution and UV exposure. This protective mechanism may help preserve skin integrity and support the skin's natural defence systems.

Clinical Evidence & References

Laboratory studies suggest that ginkgo biloba leaf extracts can protect skin cells from cytotoxicity and reduce inflammatory markers in cell cultures. Research has demonstrated that the extract's biflavone components inhibit inflammatory pathways involved in skin inflammation, which could translate to calming effects on irritated skin.

However, most existing evidence comes from in vitro and animal studies rather than human clinical trials on skin. Whilst the ingredient is recognised as safe for cosmetic use at typical concentrations, the extent of its benefits on human skin remains somewhat uncertain. Further human studies would help clarify its efficacy in real-world skincare applications.

How to Use

Ginkgo biloba leaf extract is typically used as part of a broader skincare formulation rather than as a standalone ingredient. It works well in serums, essences and moisturisers designed to soothe and protect the skin. There is no specific need to layer it separately; simply use products containing it as directed as part of your regular routine. It can be used daily and generally combines well with other active ingredients.

Safety & Precautions

Generally well-tolerated in cosmetic formulations. The safety panel has confirmed ginkgo leaf-derived ingredients are safe at typical use concentrations, though formulators should be aware of ginkgolic acid content and use good manufacturing practices to limit impurities.

Frequently Asked Questions

From the Clinic

Not sure what your skin actually needs?

Two minutes, a few questions, and we’ll point you at what matters — no guesswork.

Take the skin quiz

Part of a family

Ginkgo Biloba Leaf Cell Extract is a variant of Ginkgo Biloba Leaf Extract, the form you will most often see on an ingredients list.

Potent, plant-derived antioxidant Soothing ingredient derived from the ginkgo plant

Learn More About Skincare Ingredients

Explore our comprehensive ingredient glossary to understand what's in your products.

Browse All Ingredients

Authorised Stockist

Official UK retailer

Tracked Delivery

Free UK shipping over £50

5 Star Rating

Trusted by thousands

Expert Advice

Free consultations