Skin Conditioning

Glycyrrhiza Glabra Root

INCI: GLYCYRRHIZA GLABRA ROOT

Reviewed by Daisy · Last updated 14 Aug 2026

A traditional plant extract with emerging research into pigmentation and skin conditioning

Best For Skin Types

All

Addresses

Hyperpigmentation, Dryness, Hydration

Usage Frequency

Daily

What Is Glycyrrhiza Glabra Root?

Glycyrrhiza glabra, commonly known as liquorice or licorice, is a perennial plant native to Western Asia. The root has been used in traditional medicine for centuries, and in skincare it appears primarily as an extract containing various bioactive compounds including glabridin and liquiritin.

In cosmetic formulations, glycyrrhiza glabra root functions as a skin conditioning agent. Research suggests its active components may interact with pathways involved in melanin production, though the precise mechanisms and the extent of benefit in topical skincare remain areas of ongoing investigation.

How It Works

The extract contains multiple bioactive compounds, with glabridin and liquiritin being among the most studied. Research indicates these may interact with cellular pathways involved in melanin production, particularly through effects on CRTC1 and MITF signalling. However, the translation of these laboratory findings to real-world efficacy in topical skincare products is not yet fully established.

As a skin conditioning agent, the ingredient likely works through humectant or emollient properties, helping to support the skin's moisture retention and overall texture.

Clinical Evidence & References

Laboratory studies demonstrate that glycyrrhiza glabra extract and its isolated compounds can influence melanin production pathways in cell cultures. Some research has explored delivery methods such as nanostructured lipid carriers to potentially improve skin penetration and efficacy.

However, robust clinical evidence from human studies on the topical application of this ingredient in skincare formulations remains limited. Whilst traditional use is extensive and the ingredient appears in many products, more rigorous clinical trials would help clarify its practical benefits and optimal concentrations for cosmetic use.

How to Use

Glycyrrhiza glabra root is typically found in serums, moisturisers, and treatment products. Use as directed by your product instructions. Because it is generally well-tolerated, it can typically be used daily; however, products containing this ingredient may vary in formulation, so follow the specific guidance on your chosen product.

Safety & Precautions

Glycyrrhiza glabra root is generally considered safe for topical skincare use. Those with known sensitivity to plants in the Fabaceae family or any ingredient in the formulation should patch test first.

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Part of a family

Glycyrrhiza Glabra Root is a variant of Glycyrrhiza Glabra Root Extract, the form you will most often see on an ingredients list.

A plant extract traditionally used to address uneven skin tone and soothe irritation

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