Hydrogenated Lysophosphatidylcholine
INCI: HYDROGENATED LYSOPHOSPHATIDYLCHOLINE
Reviewed by Rosie · Last updated 2 Jun 2026
A phospholipid-derived ingredient that cleanses and stabilises formulations
Best For Skin Types
All, Sensitive, Combination
Addresses
Usage Frequency
Daily
What Is Hydrogenated Lysophosphatidylcholine?
Hydrogenated lysophosphatidylcholine is a phospholipid—a naturally occurring fatty compound found in cell membranes. In skincare, it is used as a surfactant and emulsifier, meaning it helps oil and water mix together and assists in cleansing by breaking down oils and impurities on the skin.
This ingredient is derived from or chemically similar to lysophosphatidylcholine (LPC), a compound that occurs naturally in the skin. Its primary role in formulations is functional rather than active; it helps products maintain a stable, consistent texture whilst supporting gentle cleansing action.
How It Works
As a surfactant, hydrogenated lysophosphatidylcholine works by positioning itself between oil and water molecules, allowing them to mix. This reduces the surface tension of water, enabling it to penetrate and lift away sebum, makeup, and debris from the skin's surface.
Because this ingredient is structurally similar to phospholipids naturally present in skin, it is thought to interact gently with the skin barrier rather than disrupting it, making it a preferred choice for cleansers designed for compromised or sensitive skin.
Clinical Evidence & References
Research indicates that hydrogenated lysophosphatidylcholine performs well in foamable emulsions and shows promise in formulations designed for sensitive or inflamed skin conditions, such as those affecting the scalp. Its cleansing action appears gentle enough for delicate applications.
However, independent clinical studies specifically evaluating its skin benefits in skincare products remain limited. Most evidence comes from formulation stability studies rather than direct skin efficacy trials. More research would help clarify its long-term effects on barrier health and tolerance across different skin types.
Published Research
How to Use
This ingredient is typically found in cleansers, micellar waters, and gentle rinse-off products rather than leave-on treatments. Use as directed by the product instructions, usually once or twice daily. Because it is primarily a functional ingredient, its efficacy depends on the overall formulation and other supporting ingredients present.
Safety & Precautions
Frequently Asked Questions
From the Clinic
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