Skin Conditioning

Hydrolyzed Beta-Glucan

INCI: HYDROLYZED BETA-GLUCAN

Reviewed by Daisy · Last updated 2 Jun 2026

A polysaccharide derivative that supports skin hydration and barrier function

Best For Skin Types

All, Dry, Sensitive, Combination

Addresses

Dryness, Sensitivity, Barrier repair, Redness

Effective Concentrations

0.5-2%

Usage Frequency

Daily

What Is Hydrolyzed Beta-Glucan?

Hydrolyzed beta-glucan is a breakdown product of beta-glucans, complex carbohydrates naturally found in the cell walls of yeast, fungi, and grains. In skincare, the hydrolyzed form—broken down into smaller molecular fragments—is used for its skin-conditioning properties.

When applied topically, hydrolyzed beta-glucan works primarily as a humectant and skin protectant, helping to draw moisture into the skin and support the skin barrier. It is gentle and suitable for most skin types, making it a common inclusion in moisturisers, serums, and barrier-repair products.

How It Works

Hydrolyzed beta-glucan functions as a humectant, meaning it absorbs water from the environment and from deeper skin layers, drawing it into the outer layers where it is needed most. Its molecular structure allows it to sit on the skin surface and within the stratum corneum, creating a film that helps prevent moisture loss.

Additionally, beta-glucans have been shown to interact with skin cells in ways that may promote barrier integrity. Some research suggests they can trigger mild immune responses in the skin that support healing and reduce inflammatory responses, though this effect is generally subtle when applied topically.

Clinical Evidence & References

Published research on hydrolyzed beta-glucan in skincare is limited compared to other humectants. Most evidence comes from ingredient supplier studies and in-vitro research rather than large human clinical trials. Available data suggests it is effective for increasing skin hydration and improving barrier function when used in formulations.

Its soothing and anti-inflammatory properties are supported by some studies, though the magnitude of these effects in cosmetic concentrations remains unclear. It is considered a well-tolerated ingredient with a reasonable safety profile, but more independent clinical research would help clarify its efficacy relative to other common humectants.

How to Use

Hydrolyzed beta-glucan is most effective when used in products designed to deliver hydration—such as essences, serums, or moisturisers—and works well both morning and evening. For best results, apply to damp skin to maximise its humectant effect, or layer it under an occlusive moisturiser to seal in hydration. It pairs well with other barrier-supporting ingredients such as ceramides, niacinamide, and panthenol.

Safety & Precautions

Hydrolyzed beta-glucan is generally well-tolerated and considered safe for topical use in cosmetics. It is suitable for sensitive skin. Those with specific yeast or fungal sensitivities should check product formulations, though sensitisation from beta-glucan itself is rare.

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