Humectant

Hydrolyzed Centella Asiatica Protein

INCI: HYDROLYZED CENTELLA ASIATICA PROTEIN

Reviewed by Emma · Last updated 2 Jun 2026

A protein derivative that supports skin hydration and conditioning

Best For Skin Types

All, Dry, Sensitive, Mature

Addresses

Dryness, Hydration, Sensitivity, Redness

Usage Frequency

Daily

What Is Hydrolyzed Centella Asiatica Protein?

Hydrolyzed Centella Asiatica Protein is a processed form of centella asiatica (also known as cica or gotu kola), a plant native to Asia. The protein has been broken down into smaller molecular fragments through hydrolysis, which allows it to penetrate and interact with the skin more effectively than the whole protein molecule.

In skincare formulations, this ingredient functions primarily as a humectant and skin conditioning agent. Humectants work by drawing moisture from deeper skin layers and the environment, helping to plump the skin and improve hydration at the surface.

How It Works

The hydrolyzed form of the protein is smaller and more permeable than intact proteins, allowing it to integrate into the skin rather than sit on the surface. Once in the skin, it acts as a humectant by binding water molecules and drawing them into the outer layers, which temporarily increases skin hydration and firmness.

Centella asiatica itself contains compounds (asiaticoside, madecassoside and others) that have been studied for their soothing and skin-conditioning effects, though the extent to which these remain active after hydrolysis varies depending on processing methods.

Clinical Evidence & References

Centella asiatica as a whole plant extract has a reasonably established history in dermatology and skincare, with evidence supporting its use for soothing and conditioning. However, specific clinical data on hydrolyzed centella asiatica protein as a discrete ingredient is limited in published literature.

Most evidence for this ingredient comes from in vitro studies and manufacturer data rather than rigorous human trials. It is generally regarded as safe and well-tolerated, but further independent research would help clarify its efficacy compared to other humectants and plant-derived conditioning agents at typical cosmetic concentrations.

How to Use

Hydrolyzed Centella Asiatica Protein works well in hydrating serums, essences, toners and moisturisers. It is typically used as part of a formula rather than in isolation, and pairs effectively with other humectants such as glycerin or hyaluronic acid. Apply to clean skin and layer other products as desired; it can be used daily.

Safety & Precautions

Generally well-tolerated across skin types. Centella asiatica has a long history of traditional use and is not commonly associated with irritation, though patch testing is recommended for those with known sensitivity to plant extracts.

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