Isodecyl Neopentanoate
Reviewed by Rosie · Last updated 18 Aug 2026
Also known as: Ester, Octyldodecyl Neopentanoate
Synthetic emollient that also helps product flow | Delivers silicone-like esthetics with a light, dry finish
Addresses
EWG Safety Score
What Is Isodecyl Neopentanoate?
Isodecyl neopentanoate is a synthetic emollient ester made from fatty alcohols and the short-chain fatty acid neopentanoic acid. It has silicone-like aesthetics and is used for a wide variety of purposes in cosmetics, including as an emollient. In addition, it leaves a dry, silky finish and can help deliver oil-soluble ingredients in to skin’s uppermost layers.
Isodecyl neopentanoate also works to modify the rheology of cosmetic formulas, which is a fancy way to say it can positively impact a product’s flow, such as how quickly a sunscreen or shampoo is dispensed (does it flow freely or do you really have to work to get product out?).
Usage levels of isodecyl neopentanoate in cosmetics ranges from 5–10%, although amounts lower than this may be present when this ingredient is part of a blend. It has been evaluated and deemed safe as used in cosmetics, assuming such products are formulated to be non-irritating.
Clinical Evidence & References
Published Research
-
Annals of Dermatology and Venerology, June 2021, pages 77–93 [https://doi.org/10.1016/j.annder.2020.04.027]
-
International Journal of Toxicology, September 2015, pages 5S–69S [https://doi.org/10.1177/1091581815594027]
-
UL Prospector, accessed December 2022 [URL not found]
From the Clinic
Not sure what your skin actually needs?
Two minutes, a few questions, and we’ll point you at what matters — no guesswork.
Take the skin quizRelated Ingredients
Isoamyl Laurate
Skin-softening emollient that imparts a lightweight, velvety feel | Enhances the spreadability of a formula
Isocetyl Alcohol
A lightweight conditioning agent that softens skin and adjusts product texture
Isocetyl Stearoyl Stearate
A synthetic emollient that conditions skin and regulates product texture
Isodecyl Salicylate
Ester of decyl alcohol + salicylic acid | Skin conditioning ingredient
Isomerized Jojoba Oil
A lightweight oil derived from jojoba that conditions and softens the skin
Isononyl Isononanoate
Synthetic ester that functions as an emollient skin-softening agent
Learn More About Skincare Ingredients
Explore our comprehensive ingredient glossary to understand what's in your products.
Browse All IngredientsShop Our Products
Find professional skincare solutions at Skintique.