Skin Conditioning

Ligusticum Chuanxiong Extract

INCI: LIGUSTICUM CHUANXIONG EXTRACT

Reviewed by Rosie · Last updated 2 Jun 2026

A plant extract traditionally used in Chinese medicine with emerging research on skin permeation

Best For Skin Types

All

Usage Frequency

Daily

What Is Ligusticum Chuanxiong Extract?

Ligusticum chuanxiong extract comes from the rhizome (underground stem) of Ligusticum chuanxiong, a plant native to China with a long history in traditional medicine and culinary use. The extract contains several active compounds, including ligustilide and ferulic acid, which are thought to be responsible for its biological activity.

In skincare, this ingredient functions as a skin conditioner. Research suggests it may influence how substances move through the skin barrier, though its role in cosmetic formulations is still being explored.

How It Works

The extract appears to work primarily by affecting how the skin barrier functions. Studies suggest its active compounds may temporarily enhance the skin's ability to absorb other ingredients, making it useful as a supporting ingredient in formulations designed to deliver other actives more effectively.

The mechanism is not yet fully characterised in cosmetic contexts, though research indicates the effect is concentration-dependent and more pronounced at higher levels in formulations.

Clinical Evidence & References

Research into Ligusticum chuanxiong extract's effects on skin permeation shows promising results. Studies using animal models demonstrated that the extract can significantly enhance the absorption of active compounds through skin, with some research suggesting it may be as effective as established permeation enhancers at lower concentrations.

However, evidence is primarily limited to laboratory and animal studies. Human clinical data on its efficacy and tolerability in skincare products remains limited, so its practical benefits in cosmetic use require further investigation.

How to Use

This ingredient is typically incorporated into serums, essences, and treatment products where enhanced penetration of other actives is desired. As with any new ingredient, introduce it gradually into your routine to assess tolerance, particularly if you have sensitive skin.

Safety & Precautions

Safety testing of the essential oil shows low acute toxicity and minimal skin irritation at appropriate concentrations. However, always patch test first, and discontinue use if irritation occurs.

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