Skin Conditioning

Tripotassium Glycyrrhizate

INCI: TRIPOTASSIUM GLYCYRRHIZATE

Reviewed by Daisy · Last updated 14 Aug 2026

A potassium salt derivative of liquorice root known for calming and conditioning effects

Best For Skin Types

All, Sensitive, Combination

Addresses

Sensitivity, Redness, Barrier repair

Usage Frequency

Daily

What Is Tripotassium Glycyrrhizate?

Tripotassium glycyrrhizate is a water-soluble potassium salt derived from glycyrrhizin, the active compound found in liquorice (Glycyrrhiza glabra) root. It is created through a chemical process that makes glycyrrhizin more stable and easier to formulate into skincare products.

In cosmetic formulations, it functions primarily as a skin conditioning agent, working to soothe and support the skin's natural balance. Unlike some liquorice extracts, the potassium salt form offers improved stability and consistency in product formulations.

How It Works

Tripotassium glycyrrhizate is believed to work through multiple pathways. The glycyrrhizin component interacts with skin cells in ways that may reduce inflammatory responses, making it useful in formulations aimed at calming irritation.

The potassium salt form ensures the ingredient remains stable in water-based formulations and can be absorbed by the outer layers of the skin. It does not penetrate deeply but rather conditions and protects the skin surface.

Clinical Evidence & References

Evidence for tripotassium glycyrrhizate specifically is limited, though the parent compound glycyrrhizin has been studied for its calming properties in skincare. Most research focuses on liquorice extract as a whole rather than isolated salts.

Anecdotal use and formulators' experience suggest it is well-tolerated and effective for sensitive or reactive skin, but robust clinical data comparing this ingredient to other calming agents remains sparse. Further research would strengthen claims about its efficacy.

How to Use

Tripotassium glycyrrhizate is typically found in serums, toners, moisturisers and targeted treatment products. It works well alongside other soothing ingredients and does not require special application techniques. Include it as part of your regular skincare routine; there is no need to limit frequency unless your skin shows sensitivity.

Safety & Precautions

Generally well-tolerated across skin types. Those with liquorice sensitivity or known allergen reactions should patch test first. Not known to cause phototoxicity.

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