Plant Extracts

Lithospermum Officinale Extract

INCI: LITHOSPERMUM OFFICINALE EXTRACT

Reviewed by Emma · Last updated 14 Aug 2026

A traditional herbal extract studied for its soothing and skin-protective properties

Best For Skin Types

All, Oily, Combination, Acne-prone

Addresses

Acne, Redness, Sensitivity

Effective Concentrations

0.1-0.2%

Usage Frequency

Daily

What Is Lithospermum Officinale Extract?

Lithospermum officinale extract is derived from the roots of the gromwell plant, a herb with a long history in traditional medicine systems. The extract is obtained through solvent extraction methods and contains compounds believed to have anti-inflammatory and protective effects on skin.

In skincare formulations, it functions primarily as a skin protectant and sensory agent. Its use in modern cosmetics bridges traditional botanical knowledge with contemporary skincare practice, though clinical validation in Western skincare remains limited.

How It Works

Lithospermum officinale extract appears to work through multiple mechanisms. Research suggests it inhibits the inflammatory cascade triggered by common irritants such as histamine and serotonin, which are released during inflammatory skin responses. By dampening this cascade, the extract may reduce vascular permeability and the subsequent swelling and redness that characterises inflamed skin.

The extract also seems to influence local cutaneous temperature regulation in response to inflammatory stimuli, suggesting it may interfere with the physiological markers of inflammation rather than simply masking symptoms.

Clinical Evidence & References

Clinical evidence for Lithospermum officinale extract remains sparse in Western skincare literature. A controlled trial examining herbal extracts for acne showed promise for inflammatory and non-inflammatory lesion reduction over 8 weeks, though this study examined a combination of extracts rather than Lithospermum officinale in isolation.

Pharmacological studies conducted in laboratory and animal models have demonstrated significant anti-inflammatory effects, including inhibition of chemically-induced vascular permeability and acute oedema, as well as acceleration of wound healing in rats. However, translation of these findings to human skin in clinical settings requires further investigation. The optimal concentration range appears narrow (around 0.1–0.2%), suggesting efficacy is concentration-dependent.

How to Use

Lithospermum officinale extract is typically incorporated into serums, essences, or creams as part of a multi-ingredient formula. As with any botanical extract, introduce it gradually if you have sensitive or reactive skin, and use consistently to assess benefits over 4–8 weeks. This ingredient works well alongside other skin-soothing or barrier-support ingredients, though patch testing is advisable if you have known sensitivities to plant extracts.

Safety & Precautions

Lithospermum officinale extract is generally considered well-tolerated in cosmetic formulations. No major safety concerns have been documented, though individuals with plant allergies or sensitive skin should patch test before widespread use.

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Part of a family

Lithospermum Officinale Extract is a variant of Lithospermum Officinale Root Extract, the form you will most often see on an ingredients list.

A plant extract traditionally used to support skin conditioning and comfort

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