Skin Conditioning

Morus Alba Stem Extract

INCI: MORUS ALBA STEM EXTRACT

Reviewed by Emma · Last updated 14 Aug 2026

Plant-derived antioxidant extract with potential tyrosinase-inhibiting properties

Best For Skin Types

All, Mature, Oily, Combination

Addresses

Hyperpigmentation, Oxidative stress, Dullness

Usage Frequency

Daily

What Is Morus Alba Stem Extract?

Morus alba stem extract is derived from the twigs of the mulberry tree, a plant with a long history of use in traditional medicine. The extract is prepared through hydroalcoholic processing and contains a complex mixture of naturally occurring compounds, including flavones and chalcones. These are bioactive molecules known for their antioxidant properties.

In skincare formulations, this ingredient is used as a skin conditioning agent. The extract's primary mechanism centres on its antioxidant capacity and potential to inhibit tyrosinase, an enzyme involved in melanin production.

How It Works

The extract exerts its effects through two main pathways. First, its constituent compounds (including oxyresveratrol and morachalcone A) act as antioxidants by neutralising free radicals generated by UV exposure and environmental stressors. This helps reduce oxidative damage to skin cells.

Second, several of these same compounds inhibit tyrosinase activity in laboratory studies—sometimes more effectively than the established tyrosinase inhibitor kojic acid. By slowing melanin synthesis, the extract may help address hyperpigmentation concerns, though translating in-vitro findings to in-vivo skin results requires further investigation.

Clinical Evidence & References

Research characterising mulberry twig extract has identified potent tyrosinase inhibitors within its composition. In isolated studies, compounds such as 2,4,2',4'-tetrahydroxychalcone and morachalcone A demonstrated significant inhibitory activity at very low concentrations, suggesting promising potential.

However, most existing evidence is derived from in-vitro (test-tube) studies on isolated compounds rather than clinical trials on human skin. While these findings are encouraging, direct evidence of efficacy in finished skincare products applied to the skin remains limited. Further human studies would help clarify real-world benefits and optimal formulation approaches.

How to Use

Morus alba stem extract is typically incorporated into serums, essences, and creams as one component within a broader formulation. Use as directed by the product instructions, usually as part of a daily skincare routine. Results, particularly for pigmentation concerns, may take several weeks of consistent use to become apparent. Combine with sun protection to maximise antioxidant benefits and prevent new pigmentation.

Safety & Precautions

Morus alba stem extract is generally well-tolerated in skincare products. Those with sensitivity to plant extracts or alcohol-based formulations should patch test first.

Frequently Asked Questions

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Part of a family

Morus Alba Stem Extract is a variant of Morus Alba (White Mulberry) Root Extract, the form you will most often see on an ingredients list.

Natural tyrosinase inhibitor for brightening

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