Myristyl 3-Glyceryl Ascorbate
INCI: MYRISTYL 3-GLYCERYL ASCORBATE
Reviewed by Kate · Last updated 2 Jun 2026
Also known as: Myristyl 3-glyceryl Ascorbate
A stabilised vitamin C derivative that offers antioxidant protection and gentle brightening
Best For Skin Types
All, Oily, Combination, Mature
Addresses
Usage Frequency
Daily
What Is Myristyl 3-Glyceryl Ascorbate?
Myristyl 3-glyceryl ascorbate is a lipid-soluble form of vitamin C created by bonding ascorbic acid with glycerin and myristic acid (a fatty acid). This chemical modification makes it more stable than pure vitamin C whilst allowing it to penetrate the skin's lipid barrier more effectively.
Once absorbed into the skin, the ingredient is thought to be converted into active vitamin C, where it can function as an antioxidant and support skin brightening. Because it's oil-soluble rather than water-soluble, it may suit formulations where standard vitamin C would be unstable or difficult to incorporate.
Benefits for Your Skin
How It Works
Myristyl 3-glyceryl ascorbate's fatty acid attachment allows it to dissolve in the skin's lipid-rich outer layer, facilitating penetration to the epidermis. Once there, cellular enzymes can cleave the compound to release active ascorbic acid.
As free vitamin C, it neutralises free radicals through its antioxidant capacity and may stimulate collagen synthesis and melanin regulation — the mechanisms behind its potential brightening effect. The glycerin portion also acts as a humectant, binding water molecules to the stratum corneum.
Clinical Evidence & References
Research on myristyl 3-glyceryl ascorbate specifically is limited. Much of the supporting evidence is extrapolated from studies on vitamin C's general benefits — including its antioxidant and brightening properties — rather than direct clinical trials of this particular ester form.
As a stabilised derivative, it is theoretically more likely to remain active in a formulation over time compared to ascorbic acid, though this doesn't guarantee superior results. Users may see gradual improvements in skin brightness and radiance with consistent application, though individual response varies. More targeted research on this ingredient would help clarify its efficacy compared to other vitamin C derivatives.
How to Use
Apply myristyl 3-glyceryl ascorbate products to clean, dry skin before moisturiser. Start with 3–4 times per week to assess tolerance, then adjust to daily use if well-tolerated. Layering with other actives (such as niacinamide) is generally compatible, but avoid mixing with unstable actives in the same step. Sun protection is essential during the day, as vitamin C can increase photosensitivity slightly.
Safety & Precautions
Frequently Asked Questions
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