Nephelium Lappaceum Leaf Extract
INCI: NEPHELIUM LAPPACEUM LEAF EXTRACT
Reviewed by Kate · Last updated 2 Jun 2026
A plant extract with traditional use in treating inflammatory skin conditions
Best For Skin Types
All, Sensitive, Dry
Addresses
Usage Frequency
Daily
What Is Nephelium Lappaceum Leaf Extract?
Nephelium lappaceum leaf extract is derived from the rambutan tree, native to Southeast Asia. The leaves have been used in traditional medicine across various cultures to address skin irritation, dryness, and inflammatory conditions.
In skincare formulations, this extract functions as a skin conditioning agent. It contains bioactive compounds including polyphenols, tannins, and flavonoids, which are thought to contribute to its potential benefits for compromised or inflamed skin.
How It Works
The extract's mechanism appears to centre on its polyphenol and tannin content. These compounds are thought to suppress inflammatory signalling pathways in skin cells and reduce the production of pro-inflammatory markers such as interleukins and prostaglandins.
The antioxidant activity may also help protect skin cells from oxidative stress, which can both trigger and perpetuate inflammatory responses. However, most research to date has been conducted in controlled laboratory settings rather than in human skin.
Clinical Evidence & References
Research suggests the extract has potential anti-inflammatory effects in cell-based models, particularly when skin has been exposed to irritants. Studies indicate it may reduce inflammatory markers and support cell viability under stress conditions.
However, evidence in human skin is currently limited. Most published work focuses on isolated extracts in laboratory conditions rather than the ingredient as formulated in skincare products. Further clinical studies on human volunteers would help establish its practical efficacy and optimal concentration for cosmetic use.
Published Research
How to Use
This ingredient is most commonly found in formulations designed for sensitive or inflamed skin. It can be used daily as part of a routine, either in serums, moisturisers, or treatment products. If you have very reactive skin, introduce it gradually and monitor for any sensitivity, though irritation is uncommon with plant extracts of this type.
Safety & Precautions
Frequently Asked Questions
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