Humectant

Oligopeptide-127 Rh-Oligopeptide-4

INCI: OLIGOPEPTIDE-127 RH-OLIGOPEPTIDE-4

Reviewed by Daisy · Last updated 18 Aug 2026

What Is Oligopeptide-127 Rh-Oligopeptide-4?

Oligopeptide-127 rh-Oligopeptide-4 is a single chain fusion peptide, produced by fermentation in E. coli. The starting gene is synthesized by the fusion of the gene from rh-Oligopeptide-4 and Oligopeptide-127. The fusion peptide contains 55 amino acids and consists of the proper sequence of the 20 standard amino acids.

Its declared cosmetic functions are emollient, humectant and skin conditioning.

Source: European Commission CosIng inventory.

From the Clinic

Not sure what your skin actually needs?

Two minutes, a few questions, and we’ll point you at what matters — no guesswork.

Take the skin quiz

Learn More About Skincare Ingredients

Explore our comprehensive ingredient glossary to understand what's in your products.

Browse All Ingredients

Authorised Stockist

Official UK retailer

Tracked Delivery

Free UK shipping over £50

5 Star Rating

Trusted by thousands

Expert Advice

Free consultations