Skin Conditioning

Orthosiphon Stamineus Extract

INCI: ORTHOSIPHON STAMINEUS EXTRACT

Reviewed by Emma · Last updated 14 Aug 2026

A plant extract studied for its potential to help regulate sebum production and reduce oily skin appearance

Best For Skin Types

Oily, Combination

Addresses

Oil control, Pore minimising

Usage Frequency

Daily

What Is Orthosiphon Stamineus Extract?

Orthosiphon stamineus extract comes from the leaves of a plant traditionally used in Asian herbal medicine, commonly brewed as a tea. In skincare formulations, it functions as a skin conditioning agent.

The extract contains active compounds that appear to influence sebum regulation at a biochemical level, making it of particular interest for those managing oily or combination skin.

How It Works

The mechanism appears to centre on the enzyme 5-α reductase type 1, which plays a role in sebum production. Research suggests that Orthosiphon stamineus extract may help reduce the expression and activity of this enzyme in skin cells, thereby moderating sebum secretion.

By lowering sebum production, the extract may help reduce the shiny, oily appearance of skin and the enlarged pores often associated with excess oil.

Clinical Evidence & References

In vitro studies (conducted in laboratory conditions) have demonstrated that Orthosiphon stamineus leaf extract can reduce 5-α reductase type 1 expression in human skin cells, and ex vivo research (using human tissue samples) has confirmed reduced enzyme activity and sebum production.

Whilst these findings are promising for oily skin management, the evidence is primarily at the laboratory stage. Further clinical trials on human volunteers would help establish the practical effectiveness and optimal concentrations for skincare use.

How to Use

This ingredient is typically found in formulations designed for oily or combination skin, such as serums, essences or lightweight moisturisers. It works well alongside other sebum-regulating ingredients. Use consistently as part of your routine, as skin conditioning benefits tend to develop with regular application.

Safety & Precautions

Orthosiphon stamineus extract is generally well-tolerated in skincare. Those taking medications metabolised by cytochrome P450 enzymes may wish to consult a healthcare professional, though topical skincare use presents minimal systemic absorption risk.

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Other forms of Orthosiphon Stamineus Extract

These appear on ingredients lists under different names but are the same substance. Orthosiphon Stamineus Extract is the common form.

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