Ozonized Olive Oil
INCI: OZONIZED OLIVE OIL
Reviewed by Kate · Last updated 20 Jul 2026
Also known as: Ozonized Olive Oil
Ozonised olive oil: an antioxidant-rich conditioning agent with emerging skin-comforting potential
Best For Skin Types
All, Dry, Sensitive, Mature
Addresses
Usage Frequency
Daily
What Is Ozonized Olive Oil?
Ozonised olive oil is olive oil that has been treated with ozone gas, a process that introduces reactive oxygen species into the oil. This modification alters the oil's chemical structure, creating compounds thought to have antimicrobial and anti-inflammatory properties. In skincare, it functions primarily as a skin conditioning agent, helping to soften and moisturise the skin barrier.
The ozonisation process is distinct from the oil's natural state, and the resulting ingredient is used in topical formulations rather than as a raw oil. Its inclusion in skincare products reflects growing interest in modified plant oils for their potential therapeutic benefits beyond basic hydration.
How It Works
Ozonisation creates reactive molecular structures within the olive oil that appear to work through multiple pathways. These compounds are thought to stimulate the skin's immune response at a local level, encouraging cellular repair and regeneration without causing irritation.
The mechanism may also involve improved circulation and nutrient delivery to affected areas, though much of the evidence for this comes from animal models or in vitro studies rather than human skin studies. How these effects translate to topical application in humans remains an area where more research is needed.
Clinical Evidence & References
Research on ozonised olive oil is emerging but remains limited in human subjects. Animal studies have shown encouraging results for wound healing, neovascularisation (formation of new blood vessels), and anti-inflammatory effects when applied topically. One study in rats demonstrated improved skin flap survival and increased growth factor expression following topical ozonised oil application.
However, most published research involves animal models or oral ingestion rather than topical human use. Whilst these findings are promising for understanding potential mechanisms, we cannot yet make confident claims about efficacy in typical skincare routines without larger human trials. The ingredient appears well-tolerated in the studies conducted, but long-term safety and efficacy data in cosmetic use remain limited.
How to Use
Ozonised olive oil is typically found in creams, serums, or oil-based formulations rather than as a standalone ingredient. Apply to clean skin as part of your regular skincare routine, following the product's instructions. Because it is an oil-based ingredient, it works well layered after water-based serums or used as an occlusive final step. If using in a treatment product, consistency matters: the emerging evidence suggests regular application over time may be more beneficial than occasional use.
Safety & Precautions
Frequently Asked Questions
From the Clinic
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Take the skin quizRelated Ingredients
Oxido Reductases
Enzymes that support skin's natural antioxidant defences and cellular function
Oxygen
A natural component of skin that supports cellular function and collagen production
Ozonized Argan Oil
Argan oil infused with ozone to enhance antioxidant and conditioning properties
Padina Pavonica Thallus Extract
A brown algae extract with skin-conditioning and antioxidant properties
Paeonia Albiflora Root Extract
A plant extract traditionally used in skincare to support skin conditioning and comfort
Paeonia Lactiflora Bark/Sap Extract
A plant extract traditionally used to support skin hydration and comfort
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