Palmitoyl Oligopeptide-70

Palmitoyl Oligopeptide-70 is a synthetic peptide—a short chain of amino acids—with a fatty acid (palmitic acid) attached to its structure. This modification, called palmitoylation, helps the ingredient penetrate the skin more effectively and remain in the upper layers where it can condition and support the skin's structure.In skincare formulations, it functions primarily as an emollient and skin conditioning agent, helping to soften the skin surface and maintain hydration. It may also be included in nail care products for similar conditioning benefits.

The peptide component of this ingredient is thought to interact with skin cells and support natural skin functions, whilst the attached fatty acid (palmitoyl group) acts as an emollient—a substance that fills small gaps on the skin surface and reduces water loss. This combination allows the ingredient to both condition the outer layers of skin and encourage hydration retention.The palmitoylation of the peptide chain may also enhance how well the ingredient is absorbed and utilised by the skin compared to unmodified peptides.

Palmitoyl Oligopeptide-70 is typically found in moisturisers, serums, and barrier repair products where it works alongside other hydrating and nourishing ingredients. There is no specific need to limit frequency of use; products containing this ingredient are generally suitable for daily application as part of your regular skincare routine. Allow time for the product to absorb fully before applying other treatments.

Palmitoyl Oligopeptide-70 is generally well-tolerated and is commonly used in products designed for sensitive skin. As with any skincare ingredient, patch test if you have known sensitivities to peptides or fatty acids.