EWG Safety Score
What Is Pentylene Glycol?
Pentylene glycol is an ingredient which is found naturally in some plants (such as sugar beets and corn cobs) but is most frequently lab-derived when used in cosmetics. It is a humectant, meaning it binds well to water, making it a good hydrating agent and solvent to aid penetration of other ingredients. It also helps improve the texture of skin care formulas and has mild preservative properties when used in amounts between 1-5%.
There have been some reports that pentylene glycol (along with other glycols) is a skin sensitizer; however, as with many ingredients, the amount and how it’s used are key. In cosmetics formulations the concentration of pentylene glycol ranges from 0.001% to 5%, an amount which the Cosmetics Ingredient Review panel has deemed safe to use in leave-on products.
Clinical Evidence & References
Published Research
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Matrixyl (palmitoyl pentapeptide-4): Clinical evidence International Journal of Cosmetic Science, 2009
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Anti-wrinkle efficacy of synthetic peptides Cosmetics, 2018
How widely it's used
Regulatory information
Standardised cosmetic-ingredient identifiers used by regulators.
Show identifiers
- INCI Name
- PENTYLENE GLYCOL
- EC Number
- 226-285-3
- Function
- Skin Conditioning, Solvent
From the Clinic
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A volatile solvent used to denature or dissolve other ingredients in skincare formulations
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