1,2-Hexanediol
Reviewed by Emma · Last updated 18 Aug 2026
Also known as: Caprylyl Glycol
Synthetic multi-tasking ingredient | Works as a preservative, solvent, humectant, and texture enhancer
Addresses
EWG Safety Score
What Is 1,2-Hexanediol?
1,2-hexanediol is a synthetic preservative, solvent and moisture-binding agent used in skin care and cosmetics. As a humectant, 1,2-hexanediol works to draw moisture to skin, helping to promote hydration.
Its primary action as a preservative is against bacteria, not molds or fungi, so it would never be used as the sole preservative in a water-based formula. Because of its low molecular weight chemical structure, it is highly water soluble and can also help improve the efficacy of other preservatives.
The ingredient 1,2-hexanediol also has texture-enhancing and wetting properties when used in higher amounts, helping to create smooth-flowing gels and serums.
Usage levels of 1,2-hexanediol in cosmetics ranges from 0.5-3%. It’s supplied as a colorless liquid.
1,2-hexanediol has been reviewed by the Expert Panel for Cosmetic Ingredient Safety. The Expert Panel concluded that 1,2-hexanediol is safe as used in cosmetics and personal care products. It is considered non-sensitizing.
Outside of skin care, this ingredient is used in hair care.
Benefits for Your Skin
Clinical Evidence & References
References:
- CosmeticsInfo.org, Accessed March 2024, ePublication View Study
- International Journal of Toxicology, September-October 2012, pages 147S-168S View Study
- International Journal of Cosmetic Science, October 2011, pages 421-425 View Study
- Cutaneous and Ocular Toxicology, Volume 28, 2009, pages 23-24 View Study
Published Research
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CosmeticsInfo.org, Accessed March 2024, ePublication [https://www.cosmeticsinfo.org/ingredient/12-hexanediol/]
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International Journal of Toxicology, September-October 2012, pages 147S-168S [https://journals.sagepub.com/doi/10.1177/1091581812460409]
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International Journal of Cosmetic Science, October 2011, pages 421-425 [https://onlinelibrary.wiley.com/doi/10.1111/j.1468-2494.2011.00646.x]
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Cutaneous and Ocular Toxicology, Volume 28, 2009, pages 23-24 [https://www.tandfonline.com/doi/abs/10.1080/15569520802636082]
From the Clinic
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Take the skin quizOther forms of 1,2-Hexanediol
These appear on ingredients lists under different names but are the same substance. 1,2-Hexanediol is the common form.
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