Placental Enzymes

Placental enzymes are proteolytic enzymes derived from placental tissue. They function as natural exfoliants and conditioning agents in skincare formulations, working to break down and remove dead skin cells from the surface layer of the skin.These enzymes are typically included in products designed to improve skin texture and clarity. Unlike mechanical exfoliants, enzyme-based products work through biochemical action, making them gentler and more selective in their removal of damaged or dead skin cells.

Placental enzymes are proteases—they break peptide bonds in proteins. When applied to skin, they selectively break down the protein structures that hold dead skin cells together on the surface, allowing these cells to slough away more easily than with manual removal.This enzymatic action is gentler than physical scrubbing because it targets specific proteins rather than applying blunt mechanical force. The conditioning aspect comes from the amino acids and other compounds naturally present in the placental extract, which can help soften and hydrate the skin during exfoliation.

Enzyme products work best on clean, dry skin and are typically left on for 5–15 minutes before gentle removal with a warm, damp cloth. Most enzyme exfoliants are designed for once or twice weekly use; overuse can cause irritation. Always follow the specific product instructions, as formulations vary. Avoid using enzyme products on very inflamed, broken, or sunburned skin.

Placental enzymes are generally well-tolerated, though enzyme exfoliants can cause mild irritation, redness, or dryness in sensitive individuals. Avoid contact with eyes and do not use on compromised skin barriers.