Polyglyceryl-4 Diisostearate …
INCI: POLYGLYCERYL-4 DIISOSTEARATE/POLYHYDROXYSTEARATE/SEBACATE
Reviewed by Rosie · Last updated 14 Aug 2026
Also known as: Polyglyceryl-4 Diisostearate/polyhydroxystearate/sebacate
A synthetic emulsifier that stabilises oil and water in skincare formulations
Best For Skin Types
All
Addresses
Usage Frequency
Daily
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View all →What Is Polyglyceryl-4 Diisostearate …?
Polyglyceryl-4 Diisostearate/Polyhydroxystearate/Sebacate is a synthetic emulsifier derived from polyglycerin (a modified sugar-based compound) combined with fatty acid derivatives. It functions primarily to blend oil-soluble and water-soluble ingredients in formulations, preventing them from separating.
This ingredient belongs to the polyglyceryl ester family of emulsifiers, commonly used in skincare products to create stable creams, serums, and lotions. It appears in roughly 0.6% of skincare products on the market.
How It Works
Emulsifiers are molecules with a hydrophilic (water-loving) head and a lipophilic (oil-loving) tail. Polyglyceryl-4 Diisostearate/Polyhydroxystearate/Sebacate positions itself at the boundary between oil and water phases, reducing surface tension and allowing them to mix and remain stable.
This prevents the typical separation that would otherwise occur when oils and water-based components are combined, ensuring the product maintains a uniform consistency and texture during storage and use.
Clinical Evidence & References
Published research specific to this ingredient complex is limited. However, polyglyceryl ester emulsifiers have a long history of safe use in cosmetics and are generally recognised as effective at their intended function of stabilising formulations.
Some users report concerns about potential links to fungal acne (Malassezia), though evidence is anecdotal rather than clinical. If you have a history of fungal acne, patch testing or consulting a dermatologist before use may be prudent, but this ingredient is not established as a proven trigger.
How to Use
This ingredient is used by formulation chemists, not consumers — you won't apply it directly. Simply use products containing it as directed. If you notice any irritation or worsening of acne after introducing a product with this emulsifier, discontinue use and consider whether it might be a contributing factor for your individual skin.
Safety & Precautions
Frequently Asked Questions
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Polyglyceryl-4 Caprate
An emollient and surfactant formed by the combination of polyglycerin-4 + capric acid | As a skin-conditioning agent, it smooths and hydrates skin
Polyglyceryl-4 Caprylate
A gentle emollient and emulsifier derived from plant-based sources
Polyglyceryl-4 Cocoate
A coconut-derived emollient and emulsifier that softens and helps stabilise formulations
Polyglyceryl-4 Laurate
May be plant-derived or synthetic | Ester of a polymer of glycerin and lauric acid, present in coconut or palm oils
Polyglyceryl-4 Oleate
Ester of oleic acid and polyglycerin-4 | Emulsifying agent used to mix oil and water-based ingredients in formulas
Polyglyceryl-5 Dioleate
An emulsifier that helps blend oil and water-based ingredients in skincare formulations
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