Polygonum Multiflorum Extract
INCI: POLYGONUM MULTIFLORUM EXTRACT
Reviewed by Emma · Last updated 14 Aug 2026
Plant extract with antioxidant properties traditionally used to support skin resilience
Best For Skin Types
All
Addresses
Usage Frequency
Daily
What Is Polygonum Multiflorum Extract?
Polygonum multiflorum extract is derived from the root of Polygonum multiflorum, a plant used in traditional Chinese medicine. The extract is rich in compounds with antioxidant activity, which help neutralise free radicals that accumulate in the skin from environmental stressors like UV exposure.
In skincare formulations, this ingredient functions as a skin conditioner, helping to support the skin's natural defences against oxidative stress and environmental damage.
How It Works
The extract contains compounds that work as antioxidants, meaning they donate electrons to neutralise free radicals before they can damage skin cells and collagen. This helps reduce oxidative stress, a key mechanism in photoaging and skin damage.
Research suggests the extract may also support cellular energy production and protective glutathione pathways, which are part of the skin's own defence system against oxidative damage.
Clinical Evidence & References
In vitro studies show that Polygonum multiflorum extract demonstrates antioxidant capacity and can reduce oxidative stress in human skin cells exposed to hydrogen peroxide. Research using nanovesicles derived from the plant suggests potential benefits in combating UV-induced photoaging by alleviating oxidative stress.
However, most evidence to date comes from laboratory and cell-based studies rather than human clinical trials. Whilst the findings are promising, further research in human subjects would help establish the practical efficacy of this ingredient in skincare products at typical cosmetic concentrations.
Published Research
How to Use
Polygonum multiflorum extract is typically incorporated into serums, essences and moisturisers at low concentrations. It works well as part of a broader antioxidant regimen, particularly when combined with other protective ingredients like vitamin E or niacinamide. Use daily as part of your regular skincare routine.
Safety & Precautions
Frequently Asked Questions
From the Clinic
Not sure what your skin actually needs?
Two minutes, a few questions, and we’ll point you at what matters — no guesswork.
Take the skin quizRelated Ingredients
Polygonum Cuspidatum Extract
A plant extract traditionally used in Asian medicine with emerging antioxidant properties
Polygonum Fagopyrum Flour
A plant-derived powder that conditions and softens the skin
Polygonum Fagopyrum Seed Extract
A plant-derived conditioning agent from buckwheat seeds with traditional skincare use
Polygonum Multiflorum Root Extract
A traditional plant extract with emerging evidence for skin conditioning and pigmentation support
Polygonum Odoratum Extract
A plant extract with gentle skin-conditioning properties
Polygonum Tinctorium Leaf/Stem Extract
A plant extract traditionally used in East Asian skincare with conditioning properties
Learn More About Skincare Ingredients
Explore our comprehensive ingredient glossary to understand what's in your products.
Browse All IngredientsShop Our Products
Find professional skincare solutions at Skintique.