Polymethylsilsesquioxane
Reviewed by Daisy · Last updated 18 Aug 2026
Used as a film former and skin conditioning ingredient | Is a powder with round-shaped particles
Addresses
EWG Safety Score
What Is Polymethylsilsesquioxane?
Polymethylsilsesquioxane is a polymer formed from the condensation and hydrolysis of the silicone methyltrimethoxysilane. In cosmetics, it functions primarily as a film former and skin conditioning ingredient. It provides heat stability, water resiliency, high spreadability and slip. In its raw form, it is a powder with round particles.
In a survey of cosmetic formulations, polymethylsilsesquioxane was found to be used in amounts as high as 55.2%, but most often at concentrations of 4.9% or less. The independent Cosmetic Ingredient Review panel found that polymethylsequioxane is safe as used in cosmetics, with no evidence of toxicity or sensitization. This silicone polymer is also not known to clog pores.
Clinical Evidence & References
Published Research
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Safety Assessment of Polysilsesquioxanes as Used in Cosmetics. Final Report. Cosmetic Ingredient Review [https://www.cir-safety.org/sites/default/files/PLYSIL122017FR.pdf]
Frequently Asked Questions
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