Best For Skin Types
All, Dry, Sensitive
Addresses
Usage Frequency
Daily
What Is Poria Cocos Sclerotium Extract?
Poria Cocos Sclerotium Extract comes from the sclerotium (the dense, hardened mass) of Poria Cocos, a fungus that has been used in traditional Chinese medicine and food for over 2000 years. The extract is typically obtained through ethanol extraction and contains bioactive compounds including triterpene acids.
In skincare formulations, this ingredient functions as an astringent and is thought to work through multiple pathways related to skin hydration and barrier health. It appears in roughly 0.1% of skincare products, suggesting it remains relatively uncommon in Western formulations.
How It Works
The extract appears to work primarily by stimulating the production of aquaporin-3 (AQP3) in skin cells through the PI3K/Akt/mTOR signaling pathway. Aquaporins are water-channel proteins that facilitate water transport across cell membranes, which is critical for maintaining hydration and barrier function in the epidermis.
Additionally, the triterpene acids present in Poria Cocos—including pachymic acid and poricoic acid B—have been shown in laboratory studies to modulate inflammatory responses by inhibiting certain inflammatory pathways, though their effects in real-world skincare use remain less clearly defined.
Clinical Evidence & References
In vitro studies indicate that ethanol extracts of Poria Cocos sclerotium can upregulate aquaporin-3 expression in cultured human keratinocytes, suggesting potential for supporting skin hydration at the cellular level. This mechanism is theoretically relevant to maintaining healthy barrier function and water permeability.
Research also demonstrates that specific triterpene compounds isolated from Poria Cocos show inhibitory effects against inflammation-promoting agents in mouse skin models. However, clinical evidence in human subjects is limited, and the concentrations used in research may differ from those in cosmetic products. Further human studies would help clarify practical efficacy in skincare formulations.
How to Use
Poria Cocos Sclerotium Extract is typically incorporated into serums, toners, creams, and hydrating treatments. Since this ingredient is generally combined with other hydrating and barrier-supporting compounds, use it as directed within your regular skincare routine. It integrates well with other hydrating ingredients but no specific interaction concerns have been documented.
Safety & Precautions
Frequently Asked Questions
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Take the skin quizOther forms of Poria Cocos Sclerotium Extract
These appear on ingredients lists under different names but are the same substance. Poria Cocos Sclerotium Extract is the common form.
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