Pyrroloquinoline Quinone

Pyrroloquinoline quinone (PQQ) is a small organic compound found in foods such as fermented products, kiwifruit and green tea. In skincare formulations, it functions as an antioxidant and skin conditioning agent, helping to neutralise free radicals and support the skin's natural defence mechanisms.PQQ is notable for its potential to work at the cellular level, where it may help maintain healthy skin structure and resilience. It is typically used in concentrations that align with other antioxidant actives in skincare formulas.

PQQ operates primarily as an antioxidant, meaning it can donate electrons to unstable free radical molecules and render them inert. This process helps reduce oxidative stress — a key driver of premature ageing and skin damage. The ingredient may also support cellular energy production, which indirectly contributes to healthier skin turnover and repair.At a tissue level, research in animal models suggests PQQ may help maintain collagen organisation and skin thickness, though the precise mechanisms in human skin require further investigation.

PQQ is typically incorporated into serums, moisturisers and targeted treatments. Use as directed by your product instructions — usually once or twice daily. It pairs well with other antioxidants such as vitamin C and niacinamide, and can be layered into a standard skincare routine without particular restrictions.

PQQ is generally well-tolerated. No significant adverse effects have been reported in skincare use. As with any new ingredient, conduct a patch test if you have sensitive skin or are prone to reactive responses.