Quercus Mongolica Leaf Extract
INCI: QUERCUS MONGOLICA LEAF EXTRACT
Reviewed by Daisy · Last updated 2 Jun 2026
A plant extract with traditional use for skin inflammation and emerging evidence for acne and photoaging
Best For Skin Types
All, Oily, Combination, Acne-prone
Addresses
Usage Frequency
Daily
What Is Quercus Mongolica Leaf Extract?
Quercus mongolica leaf extract comes from the leaves of a tree native to East Asia, where it has been used in traditional Korean, Chinese and Mongolian medicine for inflammatory skin and mucosal conditions. The extract contains several bioactive phenolic compounds, most notably pedunculagin, which appear responsible for its skin-conditioning properties.
In skincare formulations, this ingredient functions as a skin conditioner, meaning it works to improve skin texture and appearance rather than acting as a preservative or emulsifier.
How It Works
The extract's main active compound, pedunculagin, works through two primary mechanisms relevant to acne. First, it inhibits the production of inflammatory markers (IL-6 and IL-8) that drive acne-related inflammation. Second, it blocks 5α-reductase, an enzyme involved in hormonal regulation within the skin, which may help reduce sebum production.
For photoaging concerns, the phenolic compounds in the extract appear to inhibit matrix metalloproteinase-1 (MMP-1), an enzyme that breaks down collagen when skin is exposed to UV radiation. By limiting MMP-1 activity, the extract may help preserve skin structure and support collagen synthesis.
Clinical Evidence & References
In vitro research shows that Quercus mongolica leaf extract and its key compounds demonstrate potent anti-inflammatory activity and enzyme inhibition comparable to reference standards used in acne and photoaging studies. These results are promising but come from laboratory rather than human skin studies.
Evidence specifically for human efficacy is currently limited. The research suggests the ingredient has genuine biological activity, but clinical trials demonstrating measurable improvements in acne or fine lines in real skin conditions have not yet been published. Further investigation in controlled human studies would strengthen confidence in its practical benefits.
Published Research
How to Use
This ingredient is typically incorporated into serums, essences or moisturisers. Since it is a conditioning agent rather than an active that requires specific timing, it can be used as part of your regular routine. If combining with other targeted treatments (such as vitamin C or retinoids), introduce them gradually to monitor your skin's response.
Safety & Precautions
Frequently Asked Questions
From the Clinic
Not sure what your skin actually needs?
Two minutes, a few questions, and we’ll point you at what matters — no guesswork.
Take the skin quizRelated Ingredients
Quaternium-80
A conditioning agent primarily used in haircare formulations
Quaternium-91
A conditioning agent primarily used in hair care formulations
Quercetin Dimethyl Ether Glucoside
A plant-derived flavonoid with potential soothing and skin-conditioning properties
Quercus Petraea Bark … Leaf Extract
An oak extract that conditions and supports skin's natural resilience
Quillaja Saponaria Wood Extract
A plant-derived skin conditioner that helps maintain skin hydration and softness
Raphanus Sativus Seed Extract
A plant extract with potential antioxidant and conditioning properties from radish seeds
Learn More About Skincare Ingredients
Explore our comprehensive ingredient glossary to understand what's in your products.
Browse All IngredientsShop Our Products
Find professional skincare solutions at Skintique.