Red 21
Reviewed by Daisy · Last updated 4 Aug 2026
Also known as: D&C Red No. 21
Synthetic pigment | Ruled safe as used in cosmetics and food products
EWG Safety Score
What Is Red 21?
Red 21 is a synthetic pigment used to add color to makeup, skin care and food products. The United States Food and Drug Administration has ruled it safe as it is used in these applications. It is also known as D&C Red No. 21, with the “D&C” designation meaning it is approved for use in drugs and cosmetics.
Clinical Evidence & References
Published Research
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FDA Color Additive Status List [https://www.fda.gov/industry/color-additive-inventories/color-additive-status-list]
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