Silicone

Silicone Quaternium-27

INCI: SILICONE QUATERNIUM-27

Reviewed by Kate · Last updated 2 Jun 2026

Also known as: Silicone Quaternium-27

A silicone-based conditioning agent that creates a smooth, non-greasy feel

Best For Skin Types

All, Oily, Combination

Addresses

Hydration

Usage Frequency

Daily

What Is Silicone Quaternium-27?

Silicone Quaternium-27 is a silicone-derived conditioning polymer used primarily in hair and personal care formulations. It belongs to a family of silicone compounds that have been safely used in cosmetic and pharmaceutical applications since the mid-20th century, where they are valued for their ability to coat and condition fibres without leaving a heavy residue.

In skincare products, this ingredient functions as a conditioning agent, helping to improve the texture and tactile sensation of formulations. It contributes to the characteristic 'silky' feel many consumers associate with modern skincare, whilst remaining non-staining and non-greasy on the skin.

How It Works

Silicone Quaternium-27 works by forming a thin, protective layer over the skin's surface. Its quaternary (charged) structure allows it to bond with the skin whilst remaining lightweight, unlike heavier occlusive ingredients. This creates a smooth feel without the heaviness associated with traditional oils or waxes.

The ingredient is particularly valued in formulations where a refined, non-greasy aesthetic is important, as it allows other active ingredients to be absorbed without leaving visible residue or build-up.

Clinical Evidence & References

Silicones, including silicone-based polymers, have an established safety profile in skincare and pharmaceutical applications spanning several decades. Research indicates that approximately 60% of modern skincare products contain some form of silicone, where they are considered safe conditioning agents.

The evidence base for Silicone Quaternium-27 specifically is limited in published literature. Most safety data relates to silicones as a broader category. No significant adverse effects have been documented in cosmetic use at typical concentrations, though individual sensitivities cannot be entirely ruled out.

How to Use

Silicone Quaternium-27 is typically incorporated into formulations at low concentrations, where it blends with other ingredients rather than being a primary active. It works well in lightweight serums, moisturisers and sunscreens where a non-greasy finish is desired. For combination or oily skin types, it can help deliver hydration without adding shine.

Safety & Precautions

Silicones are generally well-tolerated in cosmetic formulations and have a long history of safe use. Individuals with known sensitivity to silicones should avoid products containing this ingredient; discontinue use if irritation occurs.

Frequently Asked Questions

From the Clinic

Not sure what your skin actually needs?

Two minutes, a few questions, and we’ll point you at what matters — no guesswork.

Take the skin quiz

Learn More About Skincare Ingredients

Explore our comprehensive ingredient glossary to understand what's in your products.

Browse All Ingredients

Authorised Stockist

Official UK retailer

Tracked Delivery

Free UK shipping over £50

5 Star Rating

Trusted by thousands

Expert Advice

Free consultations