Silicone

Silicone Quaternium-28

INCI: SILICONE QUATERNIUM-28

Reviewed by Daisy · Last updated 2 Jun 2026

Also known as: Silicone Quaternium-28

A silicone-based conditioning agent that creates a smooth, non-greasy feel on hair and skin

Best For Skin Types

All

Usage Frequency

Daily

What Is Silicone Quaternium-28?

Silicone Quaternium-28 is a silicone-derived ingredient that belongs to a class of compounds used in cosmetics since the mid-20th century. It functions as a conditioning and film-forming agent, designed to coat the surface of hair and skin fibres to improve texture and appearance.

This ingredient is classified as a hair conditioning agent and is commonly found in formulations across the skincare and haircare industries. It contributes to the characteristic silky, smooth feel that many modern skincare and haircare products aim to deliver, without leaving a greasy or occlusive residue.

How It Works

Silicone Quaternium-28 works by forming a thin, protective layer over the skin or hair surface. This coating smooths the outer texture, fills in minor irregularities, and creates a refined appearance without penetrating deeply into the skin.

The quaternium component gives this silicone a slight positive charge, which helps it adhere to and condition the surface more effectively than unmodified silicones. This allows the ingredient to remain in place longer and provide a more durable smoothing effect.

Clinical Evidence & References

Silicones, as a broader category, have been used safely in pharmaceutical and medical applications since the 1940s, including in life-saving devices and topical formulations. Current research suggests that approximately 60% of modern skincare products contain some form of silicone, and they are generally regarded as safe conditioning agents.

However, specific clinical evidence regarding Silicone Quaternium-28's efficacy in skincare is limited. The ingredient is primarily documented for its role in hair conditioning and its sensory benefits. Further research would help clarify its specific effects on various skin concerns and its long-term tolerability profile.

How to Use

This ingredient is typically found in formulated products rather than used as a standalone treatment. It is best applied to clean, dry skin as part of your regular skincare routine. Allow the product to fully absorb before applying additional layers or makeup. If using multiple silicone-based products, monitor how your skin responds, as layering can occasionally lead to buildup in those with very sensitive or congestion-prone skin.

Safety & Precautions

Silicone Quaternium-28 is generally well-tolerated and considered safe for topical use in cosmetics. Those with silicone sensitivity or prone to product buildup should patch-test before full application.

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