Humectant

Sodium Hyaluronate Crosspolymer-5

INCI: SODIUM HYALURONATE CROSSPOLYMER-5

Reviewed by Emma · Last updated 2 Jun 2026

A modified form of hyaluronic acid designed to hold moisture and support skin hydration

Best For Skin Types

All, Dry, Sensitive, Mature

Addresses

Dryness, Hydration, Fine lines, Barrier repair

Usage Frequency

Daily

What Is Sodium Hyaluronate Crosspolymer-5?

Sodium hyaluronate crosspolymer-5 is a chemically modified version of hyaluronic acid (HA), a naturally occurring substance found in skin and connective tissue. The crosspolymer structure means the HA molecules are linked together, which alters how the ingredient behaves on and in the skin compared to standard hyaluronic acid.

This ingredient functions as both a humectant—drawing water into the skin—and an emollient, helping to condition and soften the skin's surface. Because it's a modified form, it may behave differently in terms of penetration depth and how long it remains effective on the skin.

How It Works

Sodium hyaluronate crosspolymer-5 is hygroscopic, meaning it actively attracts and binds water molecules. When applied to skin, it draws moisture from deeper layers and the environment into the epidermis, creating a plumping effect that can temporarily reduce the appearance of fine lines and improve skin texture.

The crosspolymer modification may slow down how quickly the ingredient breaks down on the skin compared to unmodified hyaluronic acid, potentially extending its hydrating effect. However, the precise depth of penetration and duration depend on multiple factors including skin hydration status, humidity levels, and formulation design.

Clinical Evidence & References

Hyaluronic acid in general has a well-established role in skin hydration and is a naturally occurring component of the skin matrix. Research supports its effectiveness as a humectant and its role in supporting skin barrier function and tissue health.

Specific clinical data on the crosspolymer-5 variant is limited in publicly available literature. The crosslinking is intended to modify performance characteristics, but comparative efficacy data versus standard hyaluronic acid is not widely documented in peer-reviewed sources. Its safety profile is considered favourable, consistent with other HA-based ingredients.

How to Use

Apply sodium hyaluronate crosspolymer-5 to damp skin for optimal hydration—the moisture on your skin provides the water that the humectant draws in. It works well in serums, essences, and hydrating toners, and can be layered under creams and oils. For best results, follow with an occlusive moisturiser to lock in hydration, particularly in dry climates.

Safety & Precautions

Sodium hyaluronate crosspolymer-5 is generally well-tolerated across most skin types. Allergic reactions and irritation are uncommon, though those with known sensitivities to hyaluronic acid or other HA derivatives should patch test first.

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