Sodium RNA
Reviewed by Kate · Last updated 18 Aug 2026
Also known as: sodium ribonucleic acid, ribonucleic acid sodium, RNA sodium
Derivative of ribonucleic acid, an acid present in all living cells | Primarily used as a skin conditioning ingredient
Addresses
EWG Safety Score
What Is Sodium RNA?
Sodium RNA is also known as sodium ribonucleic acid, ribonucleic acid sodium, and RNA sodium. Ribonucleic acid is an acid present in all living cells and helps the body with several processes, including protein synthesis. In cosmetics, sodium RNA is primarily used as a skin conditioning ingredient. There is limited study that also indicates it can exert antioxidant properties on skin and reduces signs of irritation. Most sodium RNA used in cosmetics is derived from yeast; it can also be made in a lab or derived from animals. Usage levels of sodium RNA in cosmetics have not been firmly established.
Clinical Evidence & References
Published Research
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Cosmile Europe, Accessed April 2023, Website [https://cosmileeurope.eu/inci/detail/15066/sodium-rna]
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Journal of Immunology and Allergy, December 2022, ePublication [https://www.jacionline.org/]
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Journal of Cosmetic Science, November-December 2013, pages 455-468 [https://pubmed.ncbi.nlm.nih.gov/24397883/]
From the Clinic
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Sodium Stearoyl Hyaluronate
A stabilised form of hyaluronic acid that conditions skin and hair
Solanum Lycopersicum Fruit Juice
A tomato-derived ingredient rich in carotenoids and polyphenols for antioxidant skin conditioning
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A lipid-rich plant extract that supports skin barrier function and resilience
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