Sodium Trichloroacetate
INCI: SODIUM TRICHLOROACETATE
Reviewed by Emma · Last updated 14 Aug 2026
A chemical exfoliant used in professional peeling treatments for pigmentation and texture concerns
Best For Skin Types
All
Addresses
Usage Frequency
Professional treatment only
What Is Sodium Trichloroacetate?
Sodium trichloroacetate is the salt form of trichloroacetic acid (TCA), a chemical exfoliant used primarily in clinical and professional skincare settings rather than consumer products. It works by breaking down the bonds between skin cells, prompting controlled removal of the outer layers of skin.
This ingredient is most commonly encountered in professional chemical peel formulations administered by dermatologists or trained aestheticians, rather than in at-home skincare. It has been used in dermatology for several decades as part of treatment protocols for specific skin concerns.
How It Works
Sodium trichloroacetate works by denaturing proteins in the skin's outer layers, causing controlled chemical injury that prompts the skin's natural healing response. This leads to exfoliation and the shedding of damaged or pigmented cells. The depth of penetration is dose-dependent; superficial concentrations affect only the epidermis, whilst medium-depth peels can reach the dermis.
The ingredient is typically applied by a professional who carefully monitors the reaction, timing the application to achieve the desired depth of peel without causing excessive damage. Recovery time and results vary based on peel depth.
Clinical Evidence & References
Research supports the use of trichloroacetic acid peels in dermatological practice. Clinical studies indicate that superficial and medium-depth TCA peels are effective for treating melasma as maintenance or adjunctive therapy, and for improving acne-related scarring when combined with other modalities. The ingredient has a long history of use in professional settings with documented outcomes.
However, sodium trichloroacetate is a potent ingredient with potential for adverse effects if misapplied. Its use requires professional training and should not be self-administered. Evidence supports efficacy when used by trained practitioners, but outcomes depend heavily on proper application, concentration, and skin type assessment.
How to Use
Sodium trichloroacetate should only be used under professional supervision in a clinical or aesthetic setting. It is not recommended for home use. If you are considering a professional chemical peel using this ingredient, discuss your skin concerns, healing expectations, and any photosensitivity history with your practitioner beforehand. Sun protection is essential during recovery, as newly exfoliated skin is vulnerable to UV damage.
Safety & Precautions
Frequently Asked Questions
From the Clinic
Not sure what your skin actually needs?
Two minutes, a few questions, and we’ll point you at what matters — no guesswork.
Take the skin quizRelated Ingredients
Sodium Methylparaben
A paraben preservative that prevents microbial growth in skincare formulations
Sodium Paraben
A sodium salt preservative that prevents bacterial and fungal growth in skincare formulations
Sodium Salicylate
A gentler salicylate derivative that may support collagen production with reduced irritation potential
Spilanthes Acmella Flower … Stem Extract
A botanical extract with purifying properties traditionally used in Ayurvedic skincare
Stearalkonium Chloride
A multifunctional conditioning agent used to improve product texture and stability
Steartrimonium Chloride
A quaternary ammonium compound primarily used as a conditioning and antistatic agent
Learn More About Skincare Ingredients
Explore our comprehensive ingredient glossary to understand what's in your products.
Browse All IngredientsShop Our Products
Find professional skincare solutions at Skintique.