Tetrasodium Tetracarboxymethyl Naringeninchalcone
INCI: TETRASODIUM TETRACARBOXYMETHYL NARINGENINCHALCONE
Reviewed by Kate · Last updated 2 Jun 2026
A chelated flavonoid derivative designed to condition and support skin barrier function
Best For Skin Types
All, Dry, Sensitive
Addresses
Usage Frequency
Daily
What Is Tetrasodium Tetracarboxymethyl Naringeninchalcone?
Tetrasodium tetracarboxymethyl naringeninchalcone is a modified form of naringenin, a naturally occurring flavonoid compound. The ingredient has been chemically altered and chelated with sodium to improve its stability and efficacy in skincare formulations.
It functions primarily as a skin conditioning agent, working to support the skin's natural moisture retention and structural integrity. This type of ingredient is designed to help maintain skin comfort and resilience.
How It Works
As a chelated flavonoid, this ingredient works on multiple levels. The flavonoid component can help neutralise free radicals that accumulate from environmental stressors, whilst the chelation process allows it to be more stable and bioavailable within a formulation.
The skin conditioning action likely operates through moisture-binding and film-forming mechanisms, helping to reduce transepidermal water loss and support the skin's natural barrier.
Clinical Evidence & References
Published clinical data specific to this ingredient is limited. However, flavonoid compounds are well-established in skincare research for their antioxidant and conditioning properties, and chelated derivatives are designed to improve the stability and performance of such actives.
The evidence base for this particular ingredient would benefit from more independent research to fully characterise its efficacy at typical use concentrations. Current information is largely derived from ingredient supplier data and formulation studies.
How to Use
This ingredient is typically used as part of a complete skincare routine and works well alongside other hydrating or barrier-supporting actives. It is generally incorporated into serums, moisturisers, and conditioning treatments where it can be present at levels that support overall skin health without requiring special application techniques.
Safety & Precautions
Frequently Asked Questions
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