Skin Conditioning

Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate

INCI: TETRADECYL AMINOBUTYROYLVALYLAMINOBUTYRIC UREA TRIFLUOROACETATE

Reviewed by Daisy · Last updated 14 Aug 2026

A peptide-derived conditioning agent designed to support skin hydration and comfort

Best For Skin Types

All, Dry, Mature

Addresses

Dryness, Hydration, Barrier repair

Usage Frequency

Daily

What Is Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate?

Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate is a synthetic peptide-based ingredient formulated as a skin conditioning agent. It combines a long-chain fatty compound (tetradecyl) with amino acid-derived peptide sequences, creating a molecule intended to improve skin texture and moisture retention.

This ingredient works primarily as a humectant and emollient, helping to draw moisture into the skin whilst forming a protective layer on the surface. It appears in a small proportion of skincare formulations, typically at very modest concentrations.

How It Works

The ingredient functions through two complementary mechanisms. The peptide portion mimics natural skin amino acids, signalling hydration benefits and supporting the skin's own conditioning processes. The long-chain fatty component creates an occlusive layer that prevents transepidermal water loss, helping moisture remain in the skin.

Together, these actions aim to improve skin hydration, elasticity and overall comfort without a heavy or occlusive feel.

Clinical Evidence & References

Published clinical research on this specific ingredient is limited, and most available information derives from manufacturer data and in vitro studies. These suggest the ingredient performs as intended within formulations, supporting hydration markers.

More robust human-subject studies would strengthen confidence in its efficacy claims. It appears to be well-tolerated in the formulations where it is used, though individual responses will vary.

How to Use

This ingredient is typically found in moisturisers, serums and hydrating treatments at very low concentrations, so no special application technique is needed. Use as directed by the product instructions. Results are most noticeable with consistent, daily use over several weeks.

Safety & Precautions

This ingredient is generally considered safe for topical use in skincare formulations. As with any new skincare product, patch testing is advisable if you have sensitive or reactive skin.

Frequently Asked Questions

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