Thiamine Nitrate
INCI: THIAMINE NITRATE
Reviewed by Rosie · Last updated 14 Aug 2026
A B-vitamin derivative that supports skin's natural moisture balance and conditioning
Best For Skin Types
All, Dry, Sensitive
Addresses
Usage Frequency
Daily
What Is Thiamine Nitrate?
Thiamine nitrate is the nitrate salt form of thiamine (vitamin B1), a water-soluble B-vitamin essential for cellular energy metabolism. In skincare, it functions as a skin conditioning agent, meaning it helps to soften, smooth and maintain the skin's hydration and texture.
Thiamine itself plays a role in supporting normal cellular function throughout the body. When used topically in skincare formulations, thiamine nitrate is included to help maintain skin condition and support the skin's natural barrier function, though its effects are generally considered mild and supportive rather than transformative.
How It Works
Thiamine nitrate works as a humectant and skin conditioning agent. Humectants are molecules that attract water to the skin, helping to maintain hydration levels. Additionally, thiamine supports cellular energy production (ATP synthesis), which may help skin cells function optimally and maintain their structural integrity.
As a B-vitamin, thiamine is involved in the metabolism of carbohydrates and amino acids at the cellular level. This metabolic support may contribute to overall skin health, though the specific visible effects of topical application remain modest compared to other active skincare ingredients.
Clinical Evidence & References
Direct clinical evidence specifically investigating thiamine nitrate in skincare is limited. Most of the ingredient's inclusion in formulations is based on its known role as a B-vitamin and general skin conditioning properties rather than extensive published research demonstrating visible skin improvements.
Thiamine's importance to cellular health is well-established in nutritional science, but translating this to topical skincare benefits requires further investigation. It is generally considered a gentle, supportive ingredient rather than a primary active with robust clinical backing for specific skin concerns.
How to Use
Thiamine nitrate is typically used as part of a complete skincare formula rather than as a standalone treatment. It works well in hydrating serums, moisturisers and conditioning products. Apply morning and evening as directed by the product instructions. Since it is a gentle conditioning ingredient, it pairs well with other skincare actives and does not require special timing or precautions.
Safety & Precautions
Frequently Asked Questions
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