Thiamine/Yeast Polypeptide

Thiamine/Yeast Polypeptide is a composite ingredient combining thiamine (vitamin B1) with peptides derived from yeast. Thiamine is an essential B vitamin involved in cellular metabolism and energy production, whilst yeast-derived polypeptides are short chains of amino acids that the skin can recognise and utilise.When formulated together, this ingredient functions as a skin conditioner—meaning it helps support the skin's natural moisture retention, texture, and overall resilience. It is a relatively gentle, non-irritant addition to skincare products.

Thiamine functions at a cellular level, supporting the enzymatic processes that generate energy (ATP) within skin cells. This underpins normal cellular function and skin maintenance. The yeast polypeptides work as humectants and skin-conditioning agents—they absorb and bind water, plumping the outer layers of skin and improving how supple and smooth it feels.Together, these components work synergistically to condition the skin rather than dramatically alter it. The effect is subtle but cumulative with regular use.

This ingredient works best as part of a consistent skincare routine rather than a one-off treatment. It is typically found in serums, essences, and moisturisers where it can be left in contact with the skin for extended periods. No special application technique is required—use it as directed on the product's instructions, usually after cleansing and before heavier creams or oils.

Thiamine/Yeast Polypeptide is generally well-tolerated and considered safe for all skin types, including sensitive skin. Those with a documented yeast sensitivity should review the full ingredient list or patch-test first.