Tetrapeptide-72

Tetrapeptide-72 is a short-chain peptide—a fragment of amino acids—designed to interact with skin cells. Peptides are commonly used in skincare because they can signal to the skin to support its natural maintenance and repair processes, particularly those related to structural proteins like collagen.This particular tetrapeptide is used in formulations targeting mature or ageing skin concerns, though detailed information about its specific mechanism and prevalence in products remains limited in published literature.

Peptides work by communicating with skin cells, essentially signalling them to perform their maintenance functions more effectively. Tetrapeptide-72 is believed to interact with skin cells in ways that may support the production or preservation of structural proteins, particularly collagen and elastin, which naturally diminish as we age.The skin's dermal layer naturally loses collagen and elastin over time, leading to visible loss of firmness and elasticity. By potentially stimulating these pathways, tetrapeptide-72 may help the skin maintain its structural integrity.

Tetrapeptide-72 is typically found in serums, moisturisers, and targeted treatments for mature skin. For best results, apply to clean skin before other treatments, allowing it to absorb fully. Peptide products are generally compatible with most other skincare ingredients and can be used alongside vitamin C, retinol, or niacinamide, though introduce new actives gradually to monitor tolerance.

Peptides are generally well-tolerated across skin types. As with any new skincare ingredient, perform a patch test first, particularly if you have sensitive or reactive skin.