Peptides

Tripeptide-1

Reviewed by Rosie · Last updated 18 Aug 2026

Also known as: GHK

Copper-binding peptide for skin-comforting and repair

Best For Skin Types

All

Addresses

Supports Skin Comfort, ageing, scarring, inflammation

What Is Tripeptide-1?

Tripeptide-1, also known as GHK, is a naturally occurring peptide that binds copper ions. When combined with copper (as Copper Peptide/GHK-Cu), it becomes a powerful signalling molecule for wound healing, anti-inflammation, and tissue remodelling.

This peptide is found naturally in human plasma and decreases with age. Topical application helps restore its benefits, promoting collagen synthesis, skin repair, and antioxidant enzyme production.

Benefits for Your Skin

How It Works

Also known by the acronym “GHK” for the amino acids that comprise it (glycine, histidine, and lysine), tripeptide-1 is a synthetic signal peptide known to work with copper in skin to visibly repair substances that have begun to deteriorate due to age and sun exposure. It can help “teach” damaged areas how to rebuild so skin looks and feels smoother and firmer.

Clinical Evidence & References

References:

  • Clinical, Cosmetic, and Investigational Dermatology, November 2016, pages 411-419 View Study
  • BioMed Research International, July 2015 ePublication View Study
  • Preventive Nutrition and Food Science, December 2012, pages 245-253 View Study

Frequently Asked Questions

From the Clinic

Not sure what your skin actually needs?

Two minutes, a few questions, and we’ll point you at what matters — no guesswork.

Take the skin quiz

Learn More About Skincare Ingredients

Explore our comprehensive ingredient glossary to understand what's in your products.

Browse All Ingredients

Authorised Stockist

Official UK retailer

Tracked Delivery

Free UK shipping over £50

5 Star Rating

Trusted by thousands

Expert Advice

Free consultations