Skin Conditioning

Tyrosinase

INCI: TYROSINASE

Reviewed by Kate · Last updated 14 Aug 2026

An enzyme that conditions the skin and supports its natural protective functions

Best For Skin Types

All

Addresses

Dryness, Barrier repair

Usage Frequency

Daily

What Is Tyrosinase?

Tyrosinase is an enzyme naturally present in the skin and found in various plant and microbial sources used in cosmetics. In skincare formulations, it functions primarily as a skin conditioning agent, supporting the skin's natural processes and structural integrity.

The enzyme plays a role in melanin synthesis within the skin, though its use in cosmetics is typically focused on its conditioning and skin-support properties rather than pigmentation control.

How It Works

Tyrosinase works by catalysing biochemical reactions within the skin. When formulated into products, it can support the skin's natural conditioning processes and help maintain the integrity of the stratum corneum—the outermost protective layer.

The enzyme's activity is influenced by pH, temperature, and the presence of other ingredients, which is why formulation matters in determining its efficacy in a finished product.

Clinical Evidence & References

Research into tyrosinase in cosmetic applications remains limited. Most evidence relates to its biochemical role in melanin production rather than its direct benefits when applied topically in skincare products.

While the enzyme has a well-established biological function in skin, robust clinical data demonstrating specific skincare benefits from topical tyrosinase formulations is currently sparse. Further research would help clarify its practical value in consumer skincare.

How to Use

Tyrosinase-containing products are typically used as part of a regular skincare routine. Because the enzyme's activity depends on formulation factors like pH and stability, it's best used as directed by the product instructions. Pairing with complementary skincare steps will optimise overall skin health.

Safety & Precautions

Tyrosinase is generally well-tolerated in cosmetic formulations. No significant safety concerns have been documented for topical use at typical concentrations.

Frequently Asked Questions

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