Ubiquinol

Ubiquinol is the active, reduced form of coenzyme Q10 (CoQ10), a naturally occurring compound found in mitochondria—the energy-producing centres of cells. In skincare, it functions as an antioxidant and skin-conditioning agent, helping to neutralise free radicals and support the skin's natural protective systems.Unlike its oxidised counterpart ubiquinone, ubiquinol is already in the form your skin can readily use. This makes it potentially more bioavailable in topical applications, though the evidence on absorption through skin barrier remains limited.

Ubiquinol works by donating electrons to neutralise free radicals—unstable molecules that damage skin cells and accelerate visible ageing. This antioxidant action is particularly relevant for the skin's surface lipid film, a protective layer rich in natural ubiquinol that constantly encounters oxidative stressors from UV light, pollution, and microbial activity.The ingredient also contributes to skin conditioning by supporting the health of the lipid barrier, helping maintain hydration and structural integrity over time.

Ubiquinol is typically found in serums, moisturisers, and targeted treatments. It pairs well with other antioxidants like vitamin E and vitamin C, and can be used alongside retinoids or sunscreen as part of a daily routine. Store products in cool, dark conditions to preserve stability, as ubiquinol can be susceptible to oxidation.

Ubiquinol is generally well-tolerated and non-irritating in skincare formulations. No significant safety concerns have been identified in standard cosmetic safety testing.