Vitis Vinifera (Grape) Fruit Extract
Reviewed by Kate · Last updated 18 Aug 2026
Also known as: Grape Seed Extract, Grape Seed Oil, Vitis Vinifera (Grape) Seed Extract, Vitis Vinifera (Grape) Seed Oil, Vitis Vinifera, Vitis Vinifera Fruit Extract
Extracted from the fruit of grapes
Best For Skin Types
Sensitive, All
Addresses
EWG Safety Score
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What Is Vitis Vinifera (Grape) Fruit Extract?
Vitis vinifera (grape) fruit extract comes from the fruit (generally the pulp and skin) of the vine grape. Like other components of this plant, including its leaves, stem, seeds, and oil, it has multiple benefits for skin.
How It Works
Grape extract works primarily through its polyphenol content, which can scavenge free radicals—unstable molecules that damage skin cells and accelerate visible ageing. By neutralising these molecules, the extract reduces oxidative stress within the skin.
The research also indicates the extract may influence cell signalling pathways that regulate inflammation, particularly those activated by UV radiation. This dual mechanism—antioxidant and anti-inflammatory—may help support skin resilience, though most evidence comes from laboratory studies rather than large-scale clinical trials in humans.
Clinical Evidence & References
References:
- SpecialChem, Website, Accessed April 2025 View Study
- Nutrients, February 2025, pages 1-36 View Study
- Pharmaceutics, April 2023, pages 1-21 View Study
- International Journal of Toxicology, September-October 2014, pages 48S-83S View Study
Published Research
How to Use
This ingredient is most effective when used as part of a daily skincare routine, ideally in a serum, essence, or moisturiser that you'll use consistently. Pair it with sunscreen during the day for optimal protection, as the antioxidants work best when combined with UV defence. There is no need for special precautions or cycling on and off this ingredient.
Safety & Precautions
Frequently Asked Questions
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Vitis Vinifera (Grape) Fruit Extract is a variant of Vitis Vinifera Fruit Extract, the form you will most often see on an ingredients list.
A polyphenol-rich grape extract that helps protect skin from oxidative stress
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