Tonic

Zinc Glycinate

INCI: ZINC GLYCINATE

Reviewed by Emma · Last updated 14 Aug 2026

A zinc compound that supports skin's natural antioxidant defences

Best For Skin Types

All

Addresses

Hyperpigmentation, Fine lines, Antioxidant support

Usage Frequency

Daily

What Is Zinc Glycinate?

Zinc glycinate is an organic salt formed by combining zinc with the amino acid glycine. This formulation makes zinc more stable and absorbable in skincare products compared to inorganic zinc salts. Zinc is an essential mineral that plays a structural and regulatory role in skin cells.

In cosmetic formulations, zinc glycinate primarily functions as a buffering agent, helping to stabilise pH and maintain formula integrity. Beyond this, zinc itself has been studied for its involvement in skin's own antioxidant systems.

How It Works

Zinc works at a cellular level by activating metallothionein and other antioxidant enzymes that protect skin from free radical damage. This is particularly relevant because oxidative stress—triggered by UV exposure and other environmental factors—is implicated in premature ageing and hyperpigmentation.

The glycine component enhances the bioavailability and stability of zinc in cosmetic formulations, allowing it to function more effectively within the product and on the skin.

Clinical Evidence & References

Research indicates that zinc ions may help reduce oxidative stress, which is a contributing factor in skin ageing and pigmentation concerns. Studies have explored zinc's potential role in addressing hyperpigmentation and wrinkling through its influence on antioxidant defence systems.

However, most evidence for zinc's anti-ageing benefits comes from mechanistic studies and animal models rather than large-scale human trials. The degree to which topically applied zinc glycinate penetrates skin and exerts these effects in real-world use remains an area of ongoing investigation.

How to Use

Zinc glycinate is typically incorporated into serums, moisturisers, and treatments as part of a broader skincare formula. There is no specific recommendation for standalone use frequency, as the ingredient's benefit depends on the overall formulation. Use as directed by the product instructions, usually daily as part of morning and/or evening routines.

Safety & Precautions

Zinc salts are well-tolerated in cosmetic formulations at standard concentrations. The Expert Panel for Cosmetic Ingredient Safety has concluded that zinc salts, including zinc glycinate, are safe for use in cosmetics when formulated to be non-irritating.

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