Acetyl Hexapeptide-1
INCI: N/A
Reviewed by Rosie · Last updated 18 Aug 2026
Also known as: N/A, Acetyl Hexapeptide-8, Argireline
A synthetic peptide Composed of the amino acids
Best For Skin Types
All skin types
Usage Frequency
As directed on product packaging
EWG Safety Score
Acetyl Hexapeptide-1 products at Skintique
View all →What Is Acetyl Hexapeptide-1?
Acetyl hexapeptide-1 is a synthetic peptide composed of the amino acids alanine, arginine, histidine, leucine, phenylalanine and tryptophan. It helps skin better defend itself from environmental aggressors by virtue of a calming effect. This peptide can also help promote a visibly more even skin tone by playing a role in how melanin moves through skin.
Acetyl hexapeptide is a powerful synthetic peptide commonly used in anti-wrinkle serums. It functions as both a humectant and skin-restoring ingredient, helping to address common signs of ageing. As a neurotransmitter-inhibiting peptide, it works to interrupt the appearance of expression lines, though it does not replace professional neuromodulator treatments. Research demonstrates that this peptide supports the skin's collagen production and helps preserve a firmer appearance. It also acts as a potent antioxidant, neutralising environmental free radicals that contribute to premature ageing. Benefits include reducing the appearance of fine lines and wrinkles whilst improving skin elasticity.
Clinical Evidence & References
Frequently Asked Questions
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