Acetyl Tetrapeptide-18

Acetyl Tetrapeptide-18 is a synthetic peptide—a short chain of amino acids—designed to mimic natural signalling molecules in the skin. Peptides function as messengers that communicate with skin cells, encouraging them to maintain their structural integrity and perform their essential functions.This ingredient works primarily as a skin conditioning agent, helping to support the skin's barrier function and overall resilience. It is typically used in formulations where maintaining skin hydration and softness is a priority.

Peptides like Acetyl Tetrapeptide-18 communicate with skin cells by binding to receptors on their surface. This signalling prompts cells to produce and maintain structural proteins and lipids that form the skin barrier—the outermost layer responsible for keeping moisture in and irritants out.By supporting the skin's natural lipid production and barrier integrity, this peptide helps maintain hydration levels and skin resilience, which are foundational to healthy skin appearance and function.

Acetyl Tetrapeptide-18 is typically found in serums, moisturisers, and barrier-repair products. It can be used daily as part of a regular skincare routine. It pairs well with other hydrating and conditioning ingredients, and is generally suitable for layering with other actives, though it is not itself considered a treatment-strength active.

Peptides are generally well-tolerated and suitable for most skin types, including sensitive skin. No significant safety concerns have been identified for topical use in cosmetic formulations.