Best For Skin Types
All skin types
Usage Frequency
As directed on product packaging
EWG Safety Score
What Is Acetyl Tetrapeptide-5?
A synthetic peptide that has calming, smoothing, hydrating, and firmness-enhancing benefits when applied to skin. Its calming properties are believed to reduce undereye puffiness due to fluid accumulation, such as from allergies (which is not the same as undereye bags that occur from fat pads beneath the skin slipping out of place).This peptide is also believed to interrupt a process in skin known as glycation, which can cause skin’s supportive elements to weaken, giving way to wrinkles and loss of firmness. Acetyl tetrapeptide-5 seems to step in and help skin maintain a smooth resilience that results in a more youthful look.
Clinical Evidence & References
Published Research
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Acetyl Tetrapeptide-5 (Eyeseryl): Effect on periorbital skin Journal of Cosmetic Science, 2012
Frequently Asked Questions
From the Clinic
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Acetyl Tetrapeptide-22
A peptide that supports skin's natural conditioning and resilience
Acetyl Tetrapeptide-3
A peptide designed to support skin's natural protective barrier function
Acetyl Tetrapeptide-40
A peptide that supports the skin's natural lipid production and barrier function
Acetyl Tetrapeptide-69 Amide Acetate
A peptide derivative designed to support skin conditioning and barrier function
Acetyl Tetrapeptide-71
A peptide derivative that supports skin's natural moisture and lipid balance
Acetyl Tetrapeptide-9
Signal peptide” with anti-ageing benefits Supports skin’s firmness and elasticity
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