Best For Skin Types
All skin types
Usage Frequency
As directed on product packaging
EWG Safety Score
Acetyl Tetrapeptide-9 products at Skintique
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What Is Acetyl Tetrapeptide-9?
Acetyl tetrapeptide-9 is a “signal peptide” used in skin care for its anti-ageing benefits. It works by supporting key skin components like collagen, glycosaminoglycans (GAGs), and lumican, which are essential for maintaining skin structure and elasticity. Studies indicate topical application improves skin density and firmness, for a smoother, more taut appearance.
This peptide is also touted for its hydrating and plumping effects. It is lab-engineered through a process known as acetylation (a chemical reaction that involves transforming tetrapeptide-9 into an effective agent for skin). Tetrapeptide-9 is composed of the amino acids aspartic acid, glutamine, histidine and valine.
Clinical Evidence & References
Published Research
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Acetyl Tetrapeptide-9: Collagen synthesis support Molecules, 2019
Frequently Asked Questions
From the Clinic
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Acetyl Tetrapeptide-5
Synthetic peptide Calming, smoothing, hydrating, and firmness-enhancing benefits
Acetyl Tetrapeptide-69 Amide Acetate
A peptide derivative designed to support skin conditioning and barrier function
Acetyl Tetrapeptide-71
A peptide derivative that supports skin's natural moisture and lipid balance
Acetyl Tripeptide-1
A peptide that may help protect skin cells from oxidative stress and signs of ageing
Acetyl Tripeptide-54 Amide
A peptide derivative that supports skin conditioning and moisture retention
Acetyl Tripeptide-59 Amide
A peptide-derived skin conditioning agent used in cosmetic formulations
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