Centella Asiatica Leaf Cell Extract
INCI: CENTELLA ASIATICA LEAF CELL EXTRACT
Reviewed by Emma · Last updated 20 Jul 2026
A plant extract with antioxidant properties and a history in traditional medicine
Best For Skin Types
All, Sensitive, Combination
Addresses
Usage Frequency
Daily
What Is Centella Asiatica Leaf Cell Extract?
Centella asiatica leaf cell extract is derived from a plant native to Asia, commonly known as gotu kola or Indian pennywort. This ingredient is produced through cell culture extraction methods, which isolate the active compounds from the plant leaves. The extract contains triterpenic acids—including asiatic acid and madecassic acid—which are the plant's primary bioactive constituents.
In skincare formulations, this ingredient functions as an antioxidant and skin conditioning agent. It is typically included to support skin health and address visible signs of ageing, though the extent of its efficacy varies depending on concentration and formulation.
Benefits for Your Skin
How It Works
Centella asiatica extract works primarily through its bioactive triterpenic compounds, which possess antioxidant properties. These compounds are thought to help neutralise oxidative stress—a key driver of visible ageing and skin inflammation. Additionally, research suggests these compounds may help modulate the skin's inflammatory response, particularly in keratinocytes (the most abundant skin cells).
The ingredient also functions as a humectant and skin conditioning agent, helping to improve hydration and skin texture. However, the strength of these effects depends on the concentration used and how well the active compounds are preserved in the final formulation.
Clinical Evidence & References
Safety assessments by cosmetic ingredient experts confirm that centella asiatica leaf cell extract, when formulated appropriately, is safe for use in skincare products at typical concentrations. The ingredient has been used in traditional medicine for centuries, particularly in treating inflammatory skin conditions such as atopic dermatitis.
Laboratory studies have demonstrated anti-inflammatory activity in human skin cells, and the extract's active compounds have been shown to vary significantly depending on plant origin and cultivation methods. However, most evidence for skin benefits comes from in vitro research or traditional use rather than large-scale clinical trials in humans. More robust clinical evidence would be needed to fully substantiate all claimed benefits.
How to Use
Centella asiatica leaf cell extract is typically found in serums, creams, and essences. Since it is usually one ingredient among many in a formulation, its effectiveness depends on the overall product composition and your skin's individual needs. Use as directed on the product packaging. If you have very sensitive skin or are prone to contact reactions, patch test before full application.
Safety & Precautions
Frequently Asked Questions
From the Clinic
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