Antioxidant

Centella Asiatica Callus Extract

INCI: CENTELLA ASIATICA CALLUS EXTRACT

Reviewed by Kate · Last updated 2 Jun 2026

Also known as: Centella Asiatica Callus Extract

Plant extract with antioxidant properties to support skin resilience and comfort

Best For Skin Types

All, Sensitive, Combination

Addresses

Redness, Sensitivity, Fine lines

Usage Frequency

Daily

What Is Centella Asiatica Callus Extract?

Centella Asiatica Callus Extract is derived from cultured plant tissue (callus) of Centella asiatica, a plant with a long history of use in traditional medicine. The callus culture method allows for sustainable, controlled production of the plant's active compounds at scale.

In skincare formulations, this ingredient functions as an antioxidant and skin conditioning agent. It contains phytochemicals that help protect skin cells from oxidative stress, a key driver of visible ageing and skin irritation.

How It Works

The extract works primarily through its antioxidant activity. Oxidative stress in skin cells accelerates visible ageing and can trigger inflammatory responses. The phytochemicals in Centella asiatica callus extract help boost the skin's own capacity to neutralise harmful free radicals and protect against this damage.

Additionally, the ingredient has antimicrobial and skin-conditioning properties that may support overall skin comfort and resilience, particularly in stressed or compromised skin.

Clinical Evidence & References

Research suggests that Centella asiatica extracts possess meaningful antioxidant activity and anti-ageing potential, with studies showing these compounds can help dermal fibroblasts (the cells responsible for skin structure) better withstand oxidative stress. This is a promising mechanism for anti-ageing benefit.

Safety assessments have concluded that Centella asiatica-derived ingredients, including callus extract, are safe for use in cosmetics at typical concentrations when formulated to be non-sensitising. However, large-scale clinical trials in humans remain limited, so claims should be considered preliminary.

How to Use

This ingredient is typically found in serums, moisturisers, and treatment products. It works well alongside other antioxidants and barrier-support ingredients like niacinamide or ceramides. No special application technique is needed; use as directed by your product instructions.

Safety & Precautions

Centella asiatica callus extract is generally well-tolerated. Always patch test new products if you have sensitive skin, as individual sensitivities can vary.

Frequently Asked Questions

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