Chrysin
INCI: 5
Reviewed by Kate · Last updated 18 Aug 2026
Also known as: 5, 7-dihydroxyflavone
A flavonoid plant compound with antioxidant properties
EWG Safety Score
What Is Chrysin?
Chrysin is a plant-derived compound that occurs naturally in honey, passion fruit, carrots and many types of mushrooms, among other plants. It's a type of antioxidant known as a polyphenolic flavonoid. It has a signaling ability that helps reduce oxidative stress on skin. Also known as 5,7-dihydroxyflavone, chrysin has proven to be a powerful skin soother, helping to alleviate signs of irritation and discomfort, including from very dry skin. In vitro and in vivo studies have identified a compound in chrysin known as CPD 6 that is believed to deliver the bulk of its skin-calming benefits.
Chrysin has also been shown to be valuable for reducing the look of dark circles. This is due to its ability to reduce excess melanin, which is a skin pigment whose excess accumulation around the eyes is a leading contributor to this common concern.
Last, careful formulary techniques are required to stabilize chrysin and ensure its solubility in cosmetic formulas. Without such steps, its bioavailability is low. Various methods can be used to achieve this, including the use of complex sugars known as cyclodextrins, peptides, and fatty acid-based emulsifiers.
Clinical Evidence & References
Published Research
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International Journal of Molecular Sciences, April 2021, pages 1–18 International Journal of Molecular Sciences, 2021
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International Journal of Molecular Sciences, May 2019, pages 1–17 International Journal of Molecular Sciences, 2019
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Dermatologic Therapy, July 2020, pages 1–14 Dermatologic Therapy, 2020
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Life Sciences, August 2019, ePublication Life Sciences, 2019
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Journal of the Iranian Chemical Society, July 2018, pages 2,401–2,410 Journal of the Iranian Chemical Society, 2018
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Phytochemistry, January 2018, pages 187–196 Phytochemistry, 2018
From the Clinic
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Take the skin quizOther forms of Chrysin
These appear on ingredients lists under different names but are the same substance. Chrysin is the common form.
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